Atrial Fibrillation Related and Unrelated Stroke Recurrence Among Ischemic Stroke Patients With Atrial Fibrillation
DC Field | Value | Language |
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dc.contributor.author | Kim, Bum Joon | - |
dc.contributor.author | Hwang, Yang-Ha | - |
dc.contributor.author | Park, Man-Seok | - |
dc.contributor.author | Kim, Joon-Tae | - |
dc.contributor.author | Choi, Kang-Ho | - |
dc.contributor.author | Jung, Jin-Man | - |
dc.contributor.author | Yu, Sungwook | - |
dc.contributor.author | Kim, Chi Kyung | - |
dc.contributor.author | Oh, Kyungmi | - |
dc.contributor.author | Song, Tae-Jin | - |
dc.contributor.author | Kim, Yong-Jae | - |
dc.contributor.author | Park, Kwang-Yeol | - |
dc.contributor.author | Kim, Jeong-Min | - |
dc.contributor.author | Park, Jong-Ho | - |
dc.contributor.author | Choi, Jay Chol | - |
dc.contributor.author | Chung, Jong-Won | - |
dc.contributor.author | Bang, Oh Young | - |
dc.contributor.author | Kim, Gyeong-Moon | - |
dc.contributor.author | Heo, Sung Hyuk | - |
dc.contributor.author | Seo, Woo-Keun | - |
dc.date.accessioned | 2022-02-16T19:42:35Z | - |
dc.date.available | 2022-02-16T19:42:35Z | - |
dc.date.created | 2022-01-20 | - |
dc.date.issued | 2021-10-21 | - |
dc.identifier.issn | 1664-2295 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/136019 | - |
dc.description.abstract | Background: Ischemic stroke with atrial fibrillation (AF) may recur despite appropriate treatment. It may be AF-related or AF-unrelated. We compared the factors associated with AF-related and AF-unrelated recurrences among ischemic stroke patients with AF.Methods: Patients with ischemic stroke and AF were enrolled from 11 centers in Korea. Ischemic stroke recurrence was classified as AF-related if the lesion pattern was compatible with cardioembolism without significant stenosis or as AF-unrelated if the lesion was more likely due to small vessel disease or arterial stenosis. Factors associated with stroke recurrence (AF-related and AF-unrelated) were investigated.Results: Among the 2,239 patients, 115 (5.1%) experienced recurrence (75 AF-related and 40 AF-unrelated). Factors independently associated with any stroke recurrence included AF diagnosed before stroke, small subcortical infarctions, and small scattered lesions in a single vascular territory. Type of AF was associated with the type of stroke recurrence, with persistent AF being associated with AF-related stroke [hazard ratio (HR) = 2.94, 95% confidence interval (CI) 1.69-5.26; p < 0.001]. By contrast, paroxysmal AF (HR = 3.76, 95% CI 1.56-9.04; p = 0.003), AF diagnosed before stroke (HR = 2.38, 95% CI 1.19-4.55; p = 0.014), small scattered lesions in a single vascular territory (reference: corticosubcortical lesion, HR = 3.19, 95% CI 1.18-8.63; p = 0.022), and the use of antiplatelet agents (HR = 2.11, 95% CI 1.11-4.03; p = 0.024) were independently associated with AF-unrelated stroke.Conclusion: Persistent AF was more associated with AF-related stroke recurrence, whereas paroxysmal AF was more associated with AF-unrelated stroke recurrence. A scattered lesion in a single vascular territory may predict AF-unrelated stroke recurrence. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | FRONTIERS MEDIA SA | - |
dc.subject | RISK | - |
dc.subject | OUTCOMES | - |
dc.title | Atrial Fibrillation Related and Unrelated Stroke Recurrence Among Ischemic Stroke Patients With Atrial Fibrillation | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Jung, Jin-Man | - |
dc.contributor.affiliatedAuthor | Yu, Sungwook | - |
dc.identifier.doi | 10.3389/fneur.2021.744607 | - |
dc.identifier.scopusid | 2-s2.0-85118682726 | - |
dc.identifier.wosid | 000726177400001 | - |
dc.identifier.bibliographicCitation | FRONTIERS IN NEUROLOGY, v.12 | - |
dc.relation.isPartOf | FRONTIERS IN NEUROLOGY | - |
dc.citation.title | FRONTIERS IN NEUROLOGY | - |
dc.citation.volume | 12 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalWebOfScienceCategory | Clinical Neurology | - |
dc.relation.journalWebOfScienceCategory | Neurosciences | - |
dc.subject.keywordPlus | OUTCOMES | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordAuthor | atrial fibrillation | - |
dc.subject.keywordAuthor | cardioembolic brain infarction | - |
dc.subject.keywordAuthor | recurrence | - |
dc.subject.keywordAuthor | stroke | - |
dc.subject.keywordAuthor | stroke mechanism | - |
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