Clinical and microbiological characteristics of men with nonobstructive acute pyelonephritis A multicenter retrospective observational study
DC Field | Value | Language |
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dc.contributor.author | Park, Min Gu | - |
dc.contributor.author | Cho, Sung Yong | - |
dc.contributor.author | Kwon, Se Yun | - |
dc.contributor.author | Choi, Hoon | - |
dc.contributor.author | Lee, Jeong Woo | - |
dc.date.accessioned | 2022-02-17T05:40:23Z | - |
dc.date.available | 2022-02-17T05:40:23Z | - |
dc.date.created | 2022-02-09 | - |
dc.date.issued | 2021-10-08 | - |
dc.identifier.issn | 0025-7974 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/136065 | - |
dc.description.abstract | To investigate the differences in clinical and microbiological features in men hospitalized with community-acquired (CA) and healthcare-associated (HA) nonobstructive acute pyelonephritis (APN), as well as the predictive factors associated with bacteremia. Men discharged from urological centers with nonobstructive APN were identified using an electronic medical records system. We compared the clinical and microbiological data between subjects with CA-APN and HA-APN. Of the 245 men with nonobstructive APN, 175 had CA-APN, and 70 had HA-APN. The HA group was significantly older, had a longer hospital stay, and had more underlying diseases, bacteremia, and intensive care unit admissions than the CA group. The most commonly cultured microorganism was Escherichia coli. The susceptibility of the cultured bacteria to fluoroquinolone was 68.7% in the CA group and 45.3% in the HA group (P = .005). The proportion of extended-spectrum beta-lactamase-producing bacteria was 22.7% for CA and 53.5% for HA (P < .001). The sensitivity to piperacillin/tazobactam was 94.9% for CA and 90.0% for HA, and the sensitivity to amikacin was more than 95% for both groups. The multivariate analysis revealed that an age >= 65 years and chronic liver disease were independent predictive factors for bacteremia. The incidence of antibiotic resistance and bacteremia was higher in the HA group than in the CA group. However, resistance to fluoroquinolone and the presence of extended-spectrum beta-lactamase-producing bacteria were high in both groups. Piperacillin/tazobactam and amikacin may be suitable treatment options in men with nonobstructive APN. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | - |
dc.subject | PRIMARY BILIARY-CIRRHOSIS | - |
dc.subject | ESCHERICHIA-COLI | - |
dc.subject | COMMUNITY-ONSET | - |
dc.subject | RISK-FACTORS | - |
dc.subject | BACTEREMIA | - |
dc.subject | RESISTANCE | - |
dc.subject | PROSTATITIS | - |
dc.subject | INFECTIONS | - |
dc.subject | DEFINITION | - |
dc.subject | HOSPITALS | - |
dc.title | Clinical and microbiological characteristics of men with nonobstructive acute pyelonephritis A multicenter retrospective observational study | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Choi, Hoon | - |
dc.identifier.doi | 10.1097/MD.0000000000027386 | - |
dc.identifier.scopusid | 2-s2.0-85118014997 | - |
dc.identifier.wosid | 000704071200057 | - |
dc.identifier.bibliographicCitation | MEDICINE, v.100, no.40, pp.e27386 | - |
dc.relation.isPartOf | MEDICINE | - |
dc.citation.title | MEDICINE | - |
dc.citation.volume | 100 | - |
dc.citation.number | 40 | - |
dc.citation.startPage | e27386 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.subject.keywordPlus | BACTEREMIA | - |
dc.subject.keywordPlus | COMMUNITY-ONSET | - |
dc.subject.keywordPlus | DEFINITION | - |
dc.subject.keywordPlus | ESCHERICHIA-COLI | - |
dc.subject.keywordPlus | HOSPITALS | - |
dc.subject.keywordPlus | INFECTIONS | - |
dc.subject.keywordPlus | PRIMARY BILIARY-CIRRHOSIS | - |
dc.subject.keywordPlus | PROSTATITIS | - |
dc.subject.keywordPlus | RESISTANCE | - |
dc.subject.keywordPlus | RISK-FACTORS | - |
dc.subject.keywordAuthor | antibiotic susceptibility | - |
dc.subject.keywordAuthor | bacteremia | - |
dc.subject.keywordAuthor | community-acquired | - |
dc.subject.keywordAuthor | healthcare-associated | - |
dc.subject.keywordAuthor | pyelonephritis | - |
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