Carbon Monoxide Poisoning and Developing Ischemic Heart Disease: A Nationwide Population-Based Nested Case-Control Study
DC Field | Value | Language |
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dc.contributor.author | Bahng, Yewon | - |
dc.contributor.author | Baek, Kiook | - |
dc.contributor.author | Park, Jong-Tae | - |
dc.contributor.author | Choi, Won-Jun | - |
dc.contributor.author | Kwak, Kyeongmin | - |
dc.date.accessioned | 2022-02-18T01:41:12Z | - |
dc.date.available | 2022-02-18T01:41:12Z | - |
dc.date.created | 2022-02-08 | - |
dc.date.issued | 2021-10 | - |
dc.identifier.issn | 2305-6304 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/136168 | - |
dc.description.abstract | Although there are several case reports showing that carbon monoxide (CO) poisoning causes ischemic heart disease (IHD), no large-scale epidemiological studies have shown a significant association between the two. To investigate the association between CO poisoning and IHD, a nested case-control study of 28,113 patients who experienced CO poisoning and 28,113 controls matched by sex and age was performed using the nationwide health database of South Korea. Based on a conditional logistic regression, there was a significantly higher risk of IHD among the CO poisoning group than among the control group (adjusted hazard ratio [HR], 2.16; 95% confidence interval [CI], 1.87-2.49). The risk of IHD after CO poisoning was higher among the younger age group under 40 years (adjusted HR, 4.85; 95% CI, 3.20-7.35), and it was much greater among those with comorbidities (adjusted HR, 10.69; 95% CI, 2.41-47.51). The risk of IHD was the highest within the first two years after CO poisoning (adjusted HR, 11.12; 95% CI, 4.54-27.22). Even if more than six years had passed, the risk was still significantly higher than among the control group (adjusted HR, 1.55; 95% CI, 1.27-1.89). The analyses imply that CO poisoning is associated with an increased risk of IHD.</p> | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | MDPI | - |
dc.subject | ELEVATION MYOCARDIAL-INFARCTION | - |
dc.subject | INTOXICATION | - |
dc.subject | MODERATE | - |
dc.subject | INJURY | - |
dc.title | Carbon Monoxide Poisoning and Developing Ischemic Heart Disease: A Nationwide Population-Based Nested Case-Control Study | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kwak, Kyeongmin | - |
dc.identifier.doi | 10.3390/toxics9100239 | - |
dc.identifier.scopusid | 2-s2.0-85116408024 | - |
dc.identifier.wosid | 000717121700001 | - |
dc.identifier.bibliographicCitation | TOXICS, v.9, no.10 | - |
dc.relation.isPartOf | TOXICS | - |
dc.citation.title | TOXICS | - |
dc.citation.volume | 9 | - |
dc.citation.number | 10 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Environmental Sciences & Ecology | - |
dc.relation.journalResearchArea | Toxicology | - |
dc.relation.journalWebOfScienceCategory | Environmental Sciences | - |
dc.relation.journalWebOfScienceCategory | Toxicology | - |
dc.subject.keywordPlus | ELEVATION MYOCARDIAL-INFARCTION | - |
dc.subject.keywordPlus | INJURY | - |
dc.subject.keywordPlus | INTOXICATION | - |
dc.subject.keywordPlus | MODERATE | - |
dc.subject.keywordAuthor | CO intoxication | - |
dc.subject.keywordAuthor | CO poisoning | - |
dc.subject.keywordAuthor | big data | - |
dc.subject.keywordAuthor | carbon monoxide | - |
dc.subject.keywordAuthor | cardiac dysfunction | - |
dc.subject.keywordAuthor | coronary heart disease | - |
dc.subject.keywordAuthor | ischemic heart disease | - |
dc.subject.keywordAuthor | nationwide health database | - |
dc.subject.keywordAuthor | toxic effect | - |
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