Detailed Information

Cited 0 time in webofscience Cited 0 time in scopus
Metadata Downloads

Nanoscale materials-based platforms for the treatment of bone-related diseases

Authors
Zhang, XiaodiKoo, SeyoungKim, Ji HyeonHuang, XiangangKong, NaZhang, LiqunZhou, JunXue, JiajiaHarris, Mitchel B.Tao, WeiKim, Jong Seung
Issue Date
1-9월-2021
Publisher
ELSEVIER
Keywords
2D nanomaterial; arthritis; bone cancer; bone fracture; nanoparticle; osteoporosis; scaffold
Citation
MATTER, v.4, no.9, pp.2727 - 2764
Indexed
SCIE
SCOPUS
Journal Title
MATTER
Volume
4
Number
9
Start Page
2727
End Page
2764
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/136404
DOI
10.1016/j.matt.2021.05.019
ISSN
2590-2393
Abstract
Owing to the high density of bone tissue and the complex and highly hierarchical structure, drugs used for the treatment of bone-related diseases are often not effectively concentrated at the site of the lesion. Generally, the therapeutic effect is unsatisfactory, and the long-term use of drugs causes adverse effects. Therefore, it is of great importance to explore nanotherapeutic platforms to improve bone-targeting capabilities and provide controlled release performance on demand to enhance therapeutic effects. This review aims to (1) summarize various types of recently developed nanotherapeutic platforms; (2) present representative material strategies for applying nanoplatforms for treating bone diseases based on a deeper knowledge of the biophysical structure and material-chemical composition of human osteology, and the awareness of disease pathogenesis and progression; and (3) summarize the typical multifunctional systems through a suitable combination of different cues for enhancing the treatment efficacy.
Files in This Item
There are no files associated with this item.
Appears in
Collections
College of Science > Department of Chemistry > 1. Journal Articles

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher Kim, Jong Seung photo

Kim, Jong Seung
이과대학 (화학과)
Read more

Altmetrics

Total Views & Downloads

BROWSE