Correlates of poor sleep based upon wrist actigraphy data in bipolar disorder
DC Field | Value | Language |
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dc.contributor.author | Kaufmann, Christopher N. | - |
dc.contributor.author | Lee, Ellen E. | - |
dc.contributor.author | Wing, David | - |
dc.contributor.author | Sutherland, Ashley N. | - |
dc.contributor.author | Christensen, Celestine | - |
dc.contributor.author | Ancoli-Israel, Sonia | - |
dc.contributor.author | Depp, Colin A. | - |
dc.contributor.author | Yoon, Ho-Kyoung | - |
dc.contributor.author | Soontornniyomkij, Benchawanna | - |
dc.contributor.author | Eyler, Lisa T. | - |
dc.date.accessioned | 2022-02-22T06:42:27Z | - |
dc.date.available | 2022-02-22T06:42:27Z | - |
dc.date.created | 2022-02-07 | - |
dc.date.issued | 2021-09 | - |
dc.identifier.issn | 0022-3956 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/136472 | - |
dc.description.abstract | Background: Wrist-worn actigraphy can objectively measure sleep, and has advantages over self-report, particularly for people with Bipolar Disorder (BD) for whom self-reports might be influenced by affect. Clinically useful data reduction approaches are needed to explore these complex data. Methods: We created a composite score of sleep metrics in BD based on 51 BD and 80 healthy comparison (HC) participants. Subjects wore an actigraph for up to 14 consecutive 24-h periods, and we assessed total sleep time (TST), wake after sleep onset (WASO), percent sleep (PS), and number of awakenings (NA). We focused on participants who had at least 5 nights of actigraphy data. We computed z-scores for within-person means of sleep measures for BD subjects versus HCs, which were averaged to create a composite measure. We correlated this composite with participant characteristics, and used LASSO regression to identify sleep measures best explaining variability in identified correlates. Results: Sleep measures and the composite did not differ between BDs and HCs; however, there was considerable variability in z-scores among those with BD. In BDs, the composite score was higher in women (t(49) = 2.28, p = 0.027) and those who were employed (t(34) = 2.34, p = 0.025), and positively correlated with medication load (r = 0.41, p = 0.003) while negatively correlated with Young Mania Rating Scale (YMRS; r = -0.35, p = 0.030). In LASSO regression, TST and NA best explained medication load while PS best explained employment and YMRS. Conclusion: While a composite score of sleep metrics may provide useful information about sleep quality globally, our findings suggest that selection of theory-driven sleep measures may be more clinically meaningful. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | PERGAMON-ELSEVIER SCIENCE LTD | - |
dc.subject | WAKE IDENTIFICATION | - |
dc.subject | RATING-SCALE | - |
dc.subject | DURATION | - |
dc.subject | DISTURBANCE | - |
dc.subject | DEPRESSION | - |
dc.subject | ADULTS | - |
dc.subject | METAANALYSIS | - |
dc.subject | SYMPTOMS | - |
dc.subject | INSOMNIA | - |
dc.subject | VALIDITY | - |
dc.title | Correlates of poor sleep based upon wrist actigraphy data in bipolar disorder | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Yoon, Ho-Kyoung | - |
dc.identifier.doi | 10.1016/j.jpsychires.2021.06.038 | - |
dc.identifier.scopusid | 2-s2.0-85111232695 | - |
dc.identifier.wosid | 000684569200026 | - |
dc.identifier.bibliographicCitation | JOURNAL OF PSYCHIATRIC RESEARCH, v.141, pp.385 - 389 | - |
dc.relation.isPartOf | JOURNAL OF PSYCHIATRIC RESEARCH | - |
dc.citation.title | JOURNAL OF PSYCHIATRIC RESEARCH | - |
dc.citation.volume | 141 | - |
dc.citation.startPage | 385 | - |
dc.citation.endPage | 389 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | ssci | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Psychiatry | - |
dc.relation.journalWebOfScienceCategory | Psychiatry | - |
dc.subject.keywordPlus | ADULTS | - |
dc.subject.keywordPlus | DEPRESSION | - |
dc.subject.keywordPlus | DISTURBANCE | - |
dc.subject.keywordPlus | DURATION | - |
dc.subject.keywordPlus | INSOMNIA | - |
dc.subject.keywordPlus | METAANALYSIS | - |
dc.subject.keywordPlus | RATING-SCALE | - |
dc.subject.keywordPlus | SYMPTOMS | - |
dc.subject.keywordPlus | VALIDITY | - |
dc.subject.keywordPlus | WAKE IDENTIFICATION | - |
dc.subject.keywordAuthor | Actigraphy | - |
dc.subject.keywordAuthor | Bipolar disorder | - |
dc.subject.keywordAuthor | Data reduction | - |
dc.subject.keywordAuthor | Sleep | - |
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