Malnutrition and Risk of Procedural Complications in Patients With Atrial Fibrillation Undergoing Catheter Ablation
- Authors
- Kim, Daehoon; Shim, Jaemin; Kim, Yun Gi; Yu, Hee Tae; Kim, Tae-Hoon; Uhm, Jae-Sun; Choi, Jong-Il; Joung, Boyoung; Lee, Moon-Hyoung; Kim, Young-Hoon; Pak, Hui-Nam
- Issue Date
- 25-10월-2021
- Publisher
- FRONTIERS MEDIA SA
- Keywords
- atrial fibrillation; catheter ablation; complication; malnutrition; rhythm outcome
- Citation
- FRONTIERS IN CARDIOVASCULAR MEDICINE, v.8
- Indexed
- SCIE
SCOPUS
- Journal Title
- FRONTIERS IN CARDIOVASCULAR MEDICINE
- Volume
- 8
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/136683
- DOI
- 10.3389/fcvm.2021.736042
- ISSN
- 2297-055X
- Abstract
- Background: Little is known about the prognostic value of nutritional status among patients undergoing atrial fibrillation (AF) catheter ablation (AFCA). We compared the risk of procedure-related complications and long-term rhythm outcomes of AFCA according to nutritional status.</p> Methods: We included 3,239 patients undergoing de novo AFCA in 2009-2020. Nutritional status was assessed using the controlling nutritional status (CONUT) score. The association between malnutrition and the risk of AFCA complications or long-term rhythm outcomes was evaluated. We validated the effects of malnutrition using an external cohort of 360 patients undergoing AFCA in 2013-2016.</p> Results: In the study population (26.8% women, median age: 58 years), 1,005 (31.0%) had malnutrition (CONUT scores >= 2); 991 (30.6%) had mild (CONUT 2-4) and 14 (0.4%) had moderate-to-severe (CONUT >= 5) malnutrition. The overall complication rates after AFCA were 3.3% for normal nutrition, 4.2% for mild malnutrition, and 21.4% for moderate-to-severe malnutrition. Moderate-to-severe malnutrition [odds ratio (OR) 6.456, 95% confidence interval (CI) 1.637-25.463, compared with normal nutrition], older age (OR 1.020 per 1-year increase, 95% CI 1.001-1.039), female sex (OR 1.915, 95% CI 1.302-2.817), and higher systolic blood pressure (OR 1.013 per 1-mmHg increase, 95% CI 1.000-1.026) were independent predictors for the occurrence of complications. In the validation cohort, malnutrition (CONUT >= 2) was associated with a 2.87-fold higher risk of AFCA complications (95% CI 1.174-7.033). The association between malnutrition and a higher risk of AFCA complications was consistently observed regardless of body mass index and sex. Malnutrition did not affect rhythm outcomes during the median follow-up of 40 months (clinical recurrence: 37.0% in normal nutrition vs. 36.5% in malnutrition).</p> Conclusion: Malnutrition, which is common in patients undergoing AFCA, was associated with a substantially higher risk for complications after AFCA.</p>
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Collections - Graduate School > Department of Biomedical Sciences > 1. Journal Articles
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