Comparison of in-hospital outcomes of patients with vs. without ischaemic cardiomyopathy undergoing veno-arterial-extracorporeal membrane oxygenation
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Seong, Seok-Woo | - |
dc.contributor.author | Jin, Guiyue | - |
dc.contributor.author | Kim, Mijoo | - |
dc.contributor.author | Ahn, Kye Taek | - |
dc.contributor.author | Yang, Jeong Hoon | - |
dc.contributor.author | Gwon, Hyeon-Cheol | - |
dc.contributor.author | Ko, Young-Guk | - |
dc.contributor.author | Yu, Cheol Woong | - |
dc.contributor.author | Chun, Woo Jung | - |
dc.contributor.author | Jang, Woo Jin | - |
dc.contributor.author | Kim, Hyun-Joong | - |
dc.contributor.author | Bae, Jang-Whan | - |
dc.contributor.author | Kwon, Sung Uk | - |
dc.contributor.author | Lee, Hyun-Jong | - |
dc.contributor.author | Lee, Wang Soo | - |
dc.contributor.author | Park, Sang-Don | - |
dc.contributor.author | Cho, Sung Soo | - |
dc.contributor.author | Ahn, Joong Hyun | - |
dc.contributor.author | Song, Pil Sang | - |
dc.contributor.author | Jeong, Jin-Ok | - |
dc.date.accessioned | 2022-02-26T01:41:06Z | - |
dc.date.available | 2022-02-26T01:41:06Z | - |
dc.date.created | 2022-02-09 | - |
dc.date.issued | 2021-08 | - |
dc.identifier.issn | 2055-5822 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/136938 | - |
dc.description.abstract | Aims This study aimed to investigate differences in baseline and treatment characteristics, and in-hospital mortality according to the aetiologies of cardiogenic shock in patients undergoing veno-arterial-extracorporeal membrane oxygenation (VA-ECMO). Methods and results The RESCUE registry is a multicentre, observational cohort that includes 1247 patients with cardiogenic shock from 12 centres. A total of 496 patients requiring VA-ECMO were finally selected, and the study population was stratified by cardiogenic shock aetiology [ischaemic cardiomyopathy (ICM, n = 342) and non-ICM (NICM, n = 154)]. The primary outcome of interest was in-hospital mortality. Sensitivity analyses including propensity-score matching adjustments were performed. Mean age of the entire population was 61.8 +/- 14.2, and 30.8% were women. There were significant differences in baseline characteristics; notable differences included the older age of patients with ICM (65.1 +/- 13.7 vs. 58.2 +/- 13.8, P < 0.001), preponderance of males [258 (75.4%) vs. 85 (55.2%), P < 0.001], and higher prevalence of diabetes mellitus [140 (40.9%) vs. 39 (25.3%), P = 0.001] compared with patients in the NICM aetiology group. Patients with ischaemic cardiogenic shock were more likely to have longer shock duration before VA-ECMO implantation (518.7 +/- 941.4 min vs. 292.4 +/- 707.8 min, P = 0.003) and were less likely to undergo distal limb perfusion than those with NICM [108 (31.6%) vs. 79 (51.3%), P < 0.001]. In-hospital mortality in the overall cohort was 52.2%; patients with ICM had a higher unadjusted risk of in-hospital mortality [203 (59.4%) vs. 56 (36.4%); unadjusted hazard ratio, 2.295; 95% confidence interval, 1.698-3.100; P < 0.001]. There were no significant differences in the primary outcome between the two aetiologies following propensity-score matching multiple adjustments (adjusted hazard ratio, 1.265; 95% confidence interval, 0.840-1.906; P = 0.260). Conclusions Results of the current study indicated among patients with cardiogenic shock undergoing VA-ECMO, ischaemic aetiology does not seem to impact in-hospital mortality. These findings underline that early initiation and appropriate treatment strategies of VA-ECMO for patients with ICM shock are required. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | WILEY PERIODICALS, INC | - |
dc.subject | CARDIOGENIC-SHOCK | - |
dc.subject | HEART-FAILURE | - |
dc.title | Comparison of in-hospital outcomes of patients with vs. without ischaemic cardiomyopathy undergoing veno-arterial-extracorporeal membrane oxygenation | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Yu, Cheol Woong | - |
dc.identifier.doi | 10.1002/ehf2.13481 | - |
dc.identifier.scopusid | 2-s2.0-85107927737 | - |
dc.identifier.wosid | 000662969700001 | - |
dc.identifier.bibliographicCitation | ESC HEART FAILURE, v.8, no.4, pp.3308 - 3315 | - |
dc.relation.isPartOf | ESC HEART FAILURE | - |
dc.citation.title | ESC HEART FAILURE | - |
dc.citation.volume | 8 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 3308 | - |
dc.citation.endPage | 3315 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Cardiac & Cardiovascular Systems | - |
dc.subject.keywordPlus | CARDIOGENIC-SHOCK | - |
dc.subject.keywordPlus | HEART-FAILURE | - |
dc.subject.keywordAuthor | Cardiogenic shock | - |
dc.subject.keywordAuthor | ECMO | - |
dc.subject.keywordAuthor | Ischaemic cardiomyopathy | - |
dc.subject.keywordAuthor | Non-ischaemic cardiomyopathy | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
145 Anam-ro, Seongbuk-gu, Seoul, 02841, Korea+82-2-3290-2963
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.