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Bone Conduction Capacity of Highly Porous 3D-Printed Titanium Scaffolds Based on Different Pore Designs

Authors
Lim, Ho-KyungRyu, MiyoungWoo, Su-HeonSong, In-SeokChoi, Young-JunLee, Ui-Lyong
Issue Date
7월-2021
Publisher
MDPI
Keywords
3D printing; pore design; selective laser melting; titanium scaffolds
Citation
MATERIALS, v.14, no.14
Indexed
SCIE
SCOPUS
Journal Title
MATERIALS
Volume
14
Number
14
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/137214
DOI
10.3390/ma14143892
ISSN
1996-1944
Abstract
In porous titanium scaffolds manufactured via 3D printing, the differences in bone formation according to pore design and implantation period were studied. Titanium scaffolds with three types of different pore structures (Octadense, Gyroid, and Dode) were fabricated via 3D printing using the selective laser melting method. Mechanical properties of scaffolds were investigated. Prepared specimens were inserted into both femurs of nine rabbits and their clinical characteristics were observed. Three animals were sacrificed at the 2nd, 4th, and 6th weeks, and the differences in bone formation were radiologically and histologically analyzed. The percentage of new bone and surface density in the pore structure were observed to be approximately 25% and 8 mm(2)/mm(3), respectively. There was no difference in the amount of newly formed bone according to the pore design at 2, 4, and 6 weeks. In addition, no differences in the amount of newly formed bone were observed with increasing time within the same pore design for all three designs. During the 6-week observation period, the proportion of new bones in the 3D-printed titanium scaffold was approximately 25%. Differences in bone formation according to the pore design or implantation period were not observed.
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