Multichannel near-infrared spectroscopy brain imaging system for small animals in mobile conditions
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Paik, Seung-Ho | - |
dc.contributor.author | Lee, Seung Hyun | - |
dc.contributor.author | Kim, Ju-Hee | - |
dc.contributor.author | Kang, Shin-Young | - |
dc.contributor.author | Phillips, Zephaniah, V | - |
dc.contributor.author | Choi, Youngwoon | - |
dc.contributor.author | Kim, Beop-Min | - |
dc.date.accessioned | 2022-03-04T03:41:22Z | - |
dc.date.available | 2022-03-04T03:41:22Z | - |
dc.date.created | 2022-01-20 | - |
dc.date.issued | 2021-04 | - |
dc.identifier.issn | 2329-4248 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/137699 | - |
dc.description.abstract | Significance: We propose a customized animal-specific head cap and an near-infrared spectroscopy (NIRS) system to obtain NIRS signals in mobile small animals. NIRS studies in mobile small animals provide a feasible solution for comprehensive brain function studies. Aim: We aim to develop and validate a multichannel NIRS system capable of performing functional brain imaging along with a closed-box stimulation kit for small animals in mobile conditions. Approach: The customized NIRS system uses light-weight long optical fibers, along with a customized light-weight head cap to securely attach the optical fibers to the mouse. A customized stimulation box was designed to perform various stimuli in a controlled environment. The system performance was tested in a visual stimulation task on eight anesthetized mice and eight freely moving mice. Results: Following the visual stimulation task, we observed a significant stimulation-related oxyhemoglobin (HbO) increase in the visual cortex of freely moving mice during the task. In contrast, HbO concentration did not change significantly in the visual cortex of anesthetized mice. Conclusions: We demonstrate the feasibility of a wearable, multichannel NIRS system for small animals in a less confined experimental design. (C) The Authors. Published by SPIE under a Creative Commons Attribution 4.0 Unported License. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS | - |
dc.title | Multichannel near-infrared spectroscopy brain imaging system for small animals in mobile conditions | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Seung Hyun | - |
dc.contributor.affiliatedAuthor | Choi, Youngwoon | - |
dc.contributor.affiliatedAuthor | Kim, Beop-Min | - |
dc.identifier.doi | 10.1117/1.NPh.8.2.025013 | - |
dc.identifier.wosid | 000704177600014 | - |
dc.identifier.bibliographicCitation | NEUROPHOTONICS, v.8, no.2 | - |
dc.relation.isPartOf | NEUROPHOTONICS | - |
dc.citation.title | NEUROPHOTONICS | - |
dc.citation.volume | 8 | - |
dc.citation.number | 2 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalResearchArea | Optics | - |
dc.relation.journalWebOfScienceCategory | Neurosciences | - |
dc.relation.journalWebOfScienceCategory | Optics | - |
dc.subject.keywordPlus | HEMODYNAMIC-RESPONSES | - |
dc.subject.keywordPlus | MOUSE | - |
dc.subject.keywordPlus | BEHAVIOR | - |
dc.subject.keywordPlus | RAT | - |
dc.subject.keywordPlus | STIMULATION | - |
dc.subject.keywordPlus | ANESTHESIA | - |
dc.subject.keywordPlus | CORTEX | - |
dc.subject.keywordPlus | STATE | - |
dc.subject.keywordPlus | CONNECTIVITY | - |
dc.subject.keywordPlus | POTENTIALS | - |
dc.subject.keywordAuthor | near-infrared spectroscopy | - |
dc.subject.keywordAuthor | small animals | - |
dc.subject.keywordAuthor | stimulation kit | - |
dc.subject.keywordAuthor | freely moving | - |
dc.subject.keywordAuthor | neuroimaging | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.