Stroke and systemic embolism in patients with atrial fibrillation and heart failure according to heart failure type
DC Field | Value | Language |
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dc.contributor.author | Uhm, Jae-Sun | - |
dc.contributor.author | Kim, Jun | - |
dc.contributor.author | Yu, Hee Tae | - |
dc.contributor.author | Kim, Tae-Hoon | - |
dc.contributor.author | Lee, So-Ryoung | - |
dc.contributor.author | Cha, Myung-Jin | - |
dc.contributor.author | Choi, Eue-Keun | - |
dc.contributor.author | Lee, Jung Myung | - |
dc.contributor.author | Kim, Jin-Bae | - |
dc.contributor.author | Park, Junbeom | - |
dc.contributor.author | Park, Jin-Kyu | - |
dc.contributor.author | Kang, Ki-Woon | - |
dc.contributor.author | Shim, Jaemin | - |
dc.contributor.author | Park, Hyung Wook | - |
dc.contributor.author | Lee, Young Soo | - |
dc.contributor.author | Kim, Chang-Soo | - |
dc.contributor.author | Mun, Ji Eun | - |
dc.contributor.author | Son, Nak-Hoon | - |
dc.contributor.author | Joung, Boyoung | - |
dc.date.accessioned | 2022-03-04T04:41:04Z | - |
dc.date.available | 2022-03-04T04:41:04Z | - |
dc.date.created | 2021-12-07 | - |
dc.date.issued | 2021-04 | - |
dc.identifier.issn | 2055-5822 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/137702 | - |
dc.description.abstract | Aims: This study aimed to elucidate the risk for stroke and systemic embolism (SE) in patients with atrial fibrillation and heart failure (HF) according to HF type. Methods and results: A total of 10 780 patients with atrial fibrillation were enrolled in a multicentre prospective registry and divided according to HF type: no-HF, HF with preserved ejection fraction (EF) (HFpEF), HF with mid-range EF (HFmrEF), and HF with reduced EF (HFrEF). Each group included 237 age-matched and sex-matched patients (age, 69.0 +/- 10.3 years; men, 69.6%). The baseline characteristics, cumulative incidence, and hazard ratios for stroke/SE and major bleeding were compared across the groups. Patients with HF accounted for 10.3% of the total population; HFpEF, HFmrEF, and HFrEF represented 43.7%, 23.6%, and 32.7% of the patients with HF, respectively. The CHA(2)DS(2)-VASc score was significantly higher in the HFpEF, HFmrEF, and HFrEF groups than in the no-HF group. The annual stroke/SE incidence rates were 2.8%, 0.7%, 1.1%, and 0.9% in the HFpEF, HFmrEF, HFrEF, and no-HF groups, respectively. The cumulative incidence of stroke/SE was significantly highest in the HFpEF group at 22.8 +/- 10.0 months (P = 0.020). The stroke/SE risk was higher in the HFpEF group than in the HFmrEF and HFrEF groups (hazard ratio, 3.192; 95% confidence interval, 1.039-9.810; P = 0.043). E/e' value was an independent risk factor for stroke/SE. There were no significant differences in the incidence of major bleeding across the groups. Conclusions: The stroke/SE risk was the highest in the HFpEF group and comparable between the HFmrEF and HFrEF groups. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | WILEY PERIODICALS, INC | - |
dc.title | Stroke and systemic embolism in patients with atrial fibrillation and heart failure according to heart failure type | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Shim, Jaemin | - |
dc.identifier.doi | 10.1002/ehf2.13264 | - |
dc.identifier.scopusid | 2-s2.0-85101615610 | - |
dc.identifier.wosid | 000621734400001 | - |
dc.identifier.bibliographicCitation | ESC HEART FAILURE, v.8, no.2, pp.1582 - 1589 | - |
dc.relation.isPartOf | ESC HEART FAILURE | - |
dc.citation.title | ESC HEART FAILURE | - |
dc.citation.volume | 8 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 1582 | - |
dc.citation.endPage | 1589 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Cardiac & Cardiovascular Systems | - |
dc.subject.keywordPlus | PRESERVED EJECTION FRACTION | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.subject.keywordPlus | GUIDELINE | - |
dc.subject.keywordAuthor | Atrial fibrillation | - |
dc.subject.keywordAuthor | Bleeding | - |
dc.subject.keywordAuthor | Ejection fraction | - |
dc.subject.keywordAuthor | Heart failure | - |
dc.subject.keywordAuthor | Stroke | - |
dc.subject.keywordAuthor | Systemic embolism | - |
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