The Efficacy of Pilates on Urinary Incontinence in Korean Women: A Metabolomics Approach
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kang, Gyumin | - |
dc.contributor.author | Lee, Haelim | - |
dc.contributor.author | Shin, Malsoon | - |
dc.contributor.author | Kim, Jaekwan | - |
dc.contributor.author | Lee, Sungki | - |
dc.contributor.author | Park, Youngja | - |
dc.date.accessioned | 2022-03-04T21:41:10Z | - |
dc.date.available | 2022-03-04T21:41:10Z | - |
dc.date.created | 2022-02-09 | - |
dc.date.issued | 2021-02 | - |
dc.identifier.issn | 2218-1989 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/137789 | - |
dc.description.abstract | Pilates has been known as exercise intervention that improves the function of pelvic floor muscle (PFM) associated with impacting urinary incontinence (UI). This study investigated the effect of Pilates on UI in Korean women by determining the change in functional movement of PFM (FMP) and metabolic profiles. UI group with Pilates (UIP, n = 13) participated in 8-weeks Oov Pilates program, and 8 subjects were assigned to Control and UI group with no Pilates (UINP), respectively. Before and after 8 weeks, plasma samples were collected from all participants, and ultrasonography was used to measure the functional change of PFM for calculating FMP ratio. Plasma samples were analyzed by mass spectrometry to identify the change of metabolic features. After 8-weeks intervention, FMP ratio was remarkably decreased in UIP (48.1% down arrow, p < 0.001), but not in Control and UINP (p > 0.05). In metabolic features, L-Glutamine (m/z: 147.07 [M + H](+)), L-Cystathionine (m/z: 240.09 [M + NH4](+)), L-Arginine (m/z: 197.1 [M + Na](+)), and L-1-Pyrroline-3-hydroxy-5-carboxylate (m/z: 147.07 [M + NH4](+)) were significantly elevated solely in UIP (p < 0.001). Our study elucidated that Pilates can ameliorate the FMP and enhance the specific metabolic characteristics, which was potentially associated with invigorated PFM contractility to effectively control the bladder base and continence. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | MDPI | - |
dc.title | The Efficacy of Pilates on Urinary Incontinence in Korean Women: A Metabolomics Approach | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Shin, Malsoon | - |
dc.contributor.affiliatedAuthor | Park, Youngja | - |
dc.identifier.doi | 10.3390/metabo11020118 | - |
dc.identifier.scopusid | 2-s2.0-85101871225 | - |
dc.identifier.wosid | 000622790900001 | - |
dc.identifier.bibliographicCitation | METABOLITES, v.11, no.2, pp.1 - 18 | - |
dc.relation.isPartOf | METABOLITES | - |
dc.citation.title | METABOLITES | - |
dc.citation.volume | 11 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 18 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.subject.keywordAuthor | Oov Pilates | - |
dc.subject.keywordAuthor | amino acid | - |
dc.subject.keywordAuthor | core exercise | - |
dc.subject.keywordAuthor | exercise biomarker | - |
dc.subject.keywordAuthor | exercise metabolism | - |
dc.subject.keywordAuthor | liquid chromatography-mass spectrometry (LC-MS) | - |
dc.subject.keywordAuthor | pelvic floor muscle (PFM) | - |
dc.subject.keywordAuthor | untargeted metabolomics | - |
dc.subject.keywordAuthor | urinary symptom | - |
dc.subject.keywordAuthor | xMWAS | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.