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Targeting cancer’s sweet spot: UGP2 as a therapeutic vulnerability
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Kim, S. | - |
| dc.contributor.author | Wolfe, A. | - |
| dc.contributor.author | Kim, S.E. | - |
| dc.date.accessioned | 2022-03-05T11:41:04Z | - |
| dc.date.available | 2022-03-05T11:41:04Z | - |
| dc.date.created | 2022-03-02 | - |
| dc.date.issued | 2021 | - |
| dc.identifier.issn | 2372-3556 | - |
| dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/137860 | - |
| dc.description.abstract | Understanding the mechanisms governing metabolic reprogramming that underlie potential vulnerabilities in cancer cells is key to developing novel therapeutic strategies. The catalytic enzyme UDP-glucose pyrophosphorylase 2 (UGP2) drives the production of UDP-glucose. Our recent work demonstrated the crucial role of UGP2 in cancer growth and its regulation of cellular metabolic processes. © 2021 Taylor & Francis Group, LLC. | - |
| dc.language | English | - |
| dc.language.iso | en | - |
| dc.publisher | Taylor and Francis Ltd. | - |
| dc.title | Targeting cancer’s sweet spot: UGP2 as a therapeutic vulnerability | - |
| dc.type | Article | - |
| dc.contributor.affiliatedAuthor | Kim, S.E. | - |
| dc.identifier.doi | 10.1080/23723556.2021.1990676 | - |
| dc.identifier.scopusid | 2-s2.0-85118293281 | - |
| dc.identifier.bibliographicCitation | Molecular and Cellular Oncology, v.8, no.6 | - |
| dc.relation.isPartOf | Molecular and Cellular Oncology | - |
| dc.citation.title | Molecular and Cellular Oncology | - |
| dc.citation.volume | 8 | - |
| dc.citation.number | 6 | - |
| dc.type.rims | ART | - |
| dc.type.docType | Article | - |
| dc.description.journalClass | 1 | - |
| dc.description.journalRegisteredClass | scopus | - |
| dc.subject.keywordAuthor | UDP-glucose | - |
| dc.subject.keywordAuthor | UGP2 | - |
| dc.subject.keywordAuthor | YAP | - |
| dc.subject.keywordAuthor | cancer metabolism | - |
| dc.subject.keywordAuthor | glycosylation | - |
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