Differences between Staphylococcus aureus nasal carriage and IgE-sensitization to Staphylococcus aureus enterotoxin on risk factors and effects in adult population
DC Field | Value | Language |
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dc.contributor.author | Park, Han-Ki | - |
dc.contributor.author | Yoo, Seok-Ju | - |
dc.contributor.author | Kim, Taek Soo | - |
dc.contributor.author | Kim, Byung-Keun | - |
dc.contributor.author | Jang, Sekyung | - |
dc.contributor.author | Kim, Sung Yeon | - |
dc.contributor.author | Lee, Kwan | - |
dc.date.accessioned | 2022-03-14T09:41:31Z | - |
dc.date.available | 2022-03-14T09:41:31Z | - |
dc.date.created | 2022-03-14 | - |
dc.date.issued | 2022-01-31 | - |
dc.identifier.issn | 1710-1484 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/138931 | - |
dc.description.abstract | Background Staphylococcus aureus (SA) nasal carriage (SA carriage) and IgE-sensitization to SA enterotoxin (SE IgE-sensitization) are known to be associated with chronic airway disease. Objective This study aimed to evaluate the differences in risk factors, type 2 inflammation and respiratory symptoms between SA carriage and SE IgE-sensitization. Methods We conducted a cross-sectional study of a community-based adult population to evaluate the environmental exposure and health impact of the Pohang Industrial Complex, Korea. Participants were examined based on self-reported questionnaires, nasal swab, and blood sampling. Results There were 307 participants, and the overall prevalence of SA carriage and SE IgE-sensitization was 26.1% (80/307) and 25.7% (79/307), respectively. An urban environment was significantly correlated with SA carriage, whereas age and obesity were significantly correlated with SE IgE-sensitization. SA carriage was not associated with an increase in total IgE and blood eosinophil count, whereas SE IgE-sensitization was associated with an increased total IgE and blood eosinophil count. SA carriage was significantly correlated with cough persisting for more than three weeks (OR, 3.044; 95% CI, 1.137-8.153) and sputum (OR, 2.429; 95% CI, 1.008-5.854). SE IgE-sensitization was a significant correlation with only sputum (OR, 2.452; 95% CI, 1.066-5.640). SA carriage and SE IgE-sensitization showed a synergistic effect on the prevalence of cough and sputum. Conclusion SA carriage was associated with the urban environment, and SE IgE-sensitization was associated with the elderly and obesity. SA carriage and SE IgE-sensitization had different correlation with type 2 inflammation and airway symptoms. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | BMC | - |
dc.subject | ASTHMA | - |
dc.subject | COLONIZATION | - |
dc.subject | INFLAMMATION | - |
dc.subject | COUGH | - |
dc.subject | AIR | - |
dc.title | Differences between Staphylococcus aureus nasal carriage and IgE-sensitization to Staphylococcus aureus enterotoxin on risk factors and effects in adult population | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Byung-Keun | - |
dc.identifier.doi | 10.1186/s13223-022-00648-4 | - |
dc.identifier.scopusid | 2-s2.0-85124030680 | - |
dc.identifier.wosid | 000748909700003 | - |
dc.identifier.bibliographicCitation | ALLERGY ASTHMA AND CLINICAL IMMUNOLOGY, v.18, no.1 | - |
dc.relation.isPartOf | ALLERGY ASTHMA AND CLINICAL IMMUNOLOGY | - |
dc.citation.title | ALLERGY ASTHMA AND CLINICAL IMMUNOLOGY | - |
dc.citation.volume | 18 | - |
dc.citation.number | 1 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Allergy | - |
dc.relation.journalResearchArea | Immunology | - |
dc.relation.journalWebOfScienceCategory | Allergy | - |
dc.relation.journalWebOfScienceCategory | Immunology | - |
dc.subject.keywordPlus | ASTHMA | - |
dc.subject.keywordPlus | COLONIZATION | - |
dc.subject.keywordPlus | INFLAMMATION | - |
dc.subject.keywordPlus | COUGH | - |
dc.subject.keywordPlus | AIR | - |
dc.subject.keywordAuthor | Staphylococcus aureus | - |
dc.subject.keywordAuthor | Staphylococcal enterotoxins | - |
dc.subject.keywordAuthor | Risk factors | - |
dc.subject.keywordAuthor | Immunoglobulin E | - |
dc.subject.keywordAuthor | Eosinophil | - |
dc.subject.keywordAuthor | Cough | - |
dc.subject.keywordAuthor | Sputum | - |
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