Fluorescence Turn-on Synthetic Lipid Rafts on Supramolecular Sheets and Hierarchical Concanavalin A Assembly
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김용주 | - |
dc.date.accessioned | 2022-04-08T22:40:29Z | - |
dc.date.available | 2022-04-08T22:40:29Z | - |
dc.date.created | 2022-04-08 | - |
dc.date.issued | 2019-04 | - |
dc.identifier.issn | 1861-4728 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/139686 | - |
dc.description.abstract | Here we report fluorescence turn-on synthetic lipid rafts by self-assembly of a cationic distyrylanthracene derivative on a negatively-charged sheet in an aqueous solution. First, the negatively-charged 2D membrane structure is formed by lateral associations of aromatic rods with carboxylate groups. Then, the synthetic rafts are floated on the surface of the negatively-charged sheets through electrostatic interactions. The fluorescence of the synthetic rafts is turned on due to the aggregation of the positively-charged AIE dye on the sheets, facilitating monitoring of the formation of rafts. Concanavalin A (Con A) protein can load hierarchically onto the synthetic rafts at neutral pH to provide discrete Con A aggregates with a uniform size of ≈12 nm. The uniform aggregates of Con A on the synthetic rafts can stimulate Jurkat cells with enhanced efficiency, as compared with random-sized aggregates of Con A. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | JOHN WILEY AND SONS LTDSOUTHERN GATECHICHESTER, WEST SUSSEXPO19 8SQVGORAYSKA@WILEY.COM | - |
dc.title | Fluorescence Turn-on Synthetic Lipid Rafts on Supramolecular Sheets and Hierarchical Concanavalin A Assembly | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | 김용주 | - |
dc.identifier.doi | 10.1002/asia.201900122 | - |
dc.identifier.wosid | 000462924600003 | - |
dc.identifier.bibliographicCitation | CHEMISTRY - AN ASIAN JOURNAL, v.14, no.7, pp.952 - 957 | - |
dc.relation.isPartOf | CHEMISTRY - AN ASIAN JOURNAL | - |
dc.citation.title | CHEMISTRY - AN ASIAN JOURNAL | - |
dc.citation.volume | 14 | - |
dc.citation.number | 7 | - |
dc.citation.startPage | 952 | - |
dc.citation.endPage | 957 | - |
dc.type.rims | ART | - |
dc.type.docType | Letter | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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