A Flow Microreactor System Enables Organolithium Reactions without Protecting Alkoxycarbonyl Groups
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김희진 | - |
dc.date.accessioned | 2022-04-11T18:42:32Z | - |
dc.date.available | 2022-04-11T18:42:32Z | - |
dc.date.created | 2022-04-08 | - |
dc.date.issued | 2010-09 | - |
dc.identifier.issn | 0947-6539 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/140050 | - |
dc.description.abstract | A flow microreactor system consisting of micromixers and microtube reactors provides an effective tool for the generation and reactions of aryllithiums bearing an alkoxycarbonyl group at para-, meta-, and ortho-positions. Alkyl p- and m-lithiobenzoates were generated by the I/Li exchange reaction with PhLi. The Br/Li exchange reactions with sBuLi were unsuccessful. Subsequent reactions of the resulting aryllithiums with electrophiles gave the desired products in good yields. On the other hand, alkyl o-lithiobenzoates were successfully generated by the Br/Li exchange reaction with sBuLi. Subsequent reactions with electrophiles gave the desired products in good yields. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | WILEY-V C H VERLAG GMBH | - |
dc.title | A Flow Microreactor System Enables Organolithium Reactions without Protecting Alkoxycarbonyl Groups | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | 김희진 | - |
dc.identifier.doi | 10.1002/chem.201000876 | - |
dc.identifier.bibliographicCitation | CHEMISTRY-A EUROPEAN JOURNAL, v.16, no.36, pp.11167 - 11177 | - |
dc.relation.isPartOf | CHEMISTRY-A EUROPEAN JOURNAL | - |
dc.citation.title | CHEMISTRY-A EUROPEAN JOURNAL | - |
dc.citation.volume | 16 | - |
dc.citation.number | 36 | - |
dc.citation.startPage | 11167 | - |
dc.citation.endPage | 11177 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordAuthor | aryllithium | - |
dc.subject.keywordAuthor | flash chemistry | - |
dc.subject.keywordAuthor | microreactors | - |
dc.subject.keywordAuthor | organometallic compounds | - |
dc.subject.keywordAuthor | protecting groups | - |
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