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Ginseng for Erectile Dysfunction: A Cochrane Systematic Reviewopen accessGinseng for Erectile Dysfunction: A Cochrane Systematic Review

Other Titles
Ginseng for Erectile Dysfunction: A Cochrane Systematic Review
Authors
Lee, Hye WonLee, Myeong SooKim, Tae-HunAlraek, TerjeZaslawski, ChrisKim, Jong WookMoon, Du Geon
Issue Date
4월-2022
Publisher
KOREAN SOC SEXUAL MEDICINE & ANDROLOGY
Keywords
Erectile dysfunction; Ginseng; Meta-analysis; Panax; Systematic review
Citation
WORLD JOURNAL OF MENS HEALTH, v.40, no.2, pp.264 - 269
Indexed
SCIE
SCOPUS
KCI
Journal Title
WORLD JOURNAL OF MENS HEALTH
Volume
40
Number
2
Start Page
264
End Page
269
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/142135
DOI
10.5534/wjmh.210071
ISSN
2287-4208
Abstract
The objectives of this study were to assess the effects of ginseng on erectile dysfunction. We searched multiple electronic databases from their inceptions to 30 January 2021 without restrictions by language. We included randomized or quasi randomized controlled trials that evaluated the use of any type of ginseng as a treatment for erectile dysfunction compared to placebo or conventional treatment. The authors independently screened the literature, extracted data, assessed risk of bias, and rated the certainty of evidence (CoE) according to the GRADE approach. We included nine studies, and all compared ginseng to placebo. Ginseng appears to have a trivial effect on erectile dysfunction when compared to placebo based on the Erectile Function Domain of the International Index of Erectile Function (IIEF)-15 instrument (mean difference [MD] 3.52, 95% confidence interval [CI] 1.79 to 5.25; I-2=0%; 3 studies; low CoE). Ginseng may have little to no effect on adverse events compared to placebo (risk ratio [RR] 1.45, 95% CI 0.69 to 3.03; I-2=0%; 7 studies; low CoE). While ginseng may improve men's self-reported ability to have intercourse (RR 2.55, 95% CI 1.76 to 3.69; I-2=23%; 6 studies; low CoE), it may have a trivial effect on men's satisfaction with intercourse based on the Intercourse Satisfaction Domain of the IIEF-15 (MD 1.19, 95% CI 0.41 to 1.97; I-2=0%; 3 studies; low CoE). No study reported quality of life as an outcome.
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