Impact of national Covid-19 vaccination Campaign, South Korea
DC Field | Value | Language |
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dc.contributor.author | Yi, Seonju | - |
dc.contributor.author | Choe, Young June | - |
dc.contributor.author | Lim, Do Sang | - |
dc.contributor.author | Lee, Hye Roen | - |
dc.contributor.author | Kim, Jia | - |
dc.contributor.author | Kim, Yoo-Yeon | - |
dc.contributor.author | Kim, Ryu Kyung | - |
dc.contributor.author | Jang, Eun Jung | - |
dc.contributor.author | Lee, Sangwon | - |
dc.contributor.author | Park, Eunjoo | - |
dc.contributor.author | Kim, Seung-Jin | - |
dc.contributor.author | Park, Young-Joon | - |
dc.date.accessioned | 2022-09-24T12:59:10Z | - |
dc.date.available | 2022-09-24T12:59:10Z | - |
dc.date.created | 2022-09-23 | - |
dc.date.issued | 2022-06-09 | - |
dc.identifier.issn | 0264-410X | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/143884 | - |
dc.description.abstract | Background: We evaluate the overall effectiveness of the nationwide vaccination campaign using ChAdOx1 nCoV-19, BNT162b2, mRNA-1273, and Ad26.COV2.S vaccines in preventing Covid-19 in South Korea. Methods: The National Surveillance System with the National Immunization Registry were linked to form a large-linked database for assessment. Age-adjusted incidence of SARS-CoV-2 infection, severe disease, and death by vaccination status are calculated. Weekly vaccine effectiveness was calculated based on incidence rate ratio (IRR) between fully-vaccinated and unvaccinated persons, as: IRR = incidence rate of vaccinated / incidence rate of unvaccinated. We estimate the cumulative SARS-CoV-2 outcome overtime comparing the observed case with predicted cases without vaccination. Results: Age-adjusted incidence in unvaccinated persons (5.69 per 100,000 person-day) was 2.7 times the rate in fully vaccinated (2.13 per 100,000 person-day) persons, resulting effectiveness against SARS-CoV-2 infection of 63%. Vaccine effectiveness against severe disease and death were 93% and 95%, respectively. Between March and October 2021, estimated Covid-19 related outcomes averted by vaccinations were: 46,508 infections, 3,424 severe diseases, and 718 deaths. Conclusions: We found significant protection for national Covid-19 vaccination campaign against Covid-19 severe disease, and death in target populations, but there was an unexpected decreased protection against SARS-CoV-2 infection, highlighting the importance of continued surveillance and assessment. (C) 2022 Elsevier Ltd. All rights reserved. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCI LTD | - |
dc.title | Impact of national Covid-19 vaccination Campaign, South Korea | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Choe, Young June | - |
dc.identifier.doi | 10.1016/j.vaccine.2022.05.002 | - |
dc.identifier.scopusid | 2-s2.0-85130395347 | - |
dc.identifier.wosid | 000836819800030 | - |
dc.identifier.bibliographicCitation | VACCINE, v.40, no.26, pp.3670 - 3675 | - |
dc.relation.isPartOf | VACCINE | - |
dc.citation.title | VACCINE | - |
dc.citation.volume | 40 | - |
dc.citation.number | 26 | - |
dc.citation.startPage | 3670 | - |
dc.citation.endPage | 3675 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Immunology | - |
dc.relation.journalResearchArea | Research & Experimental Medicine | - |
dc.relation.journalWebOfScienceCategory | Immunology | - |
dc.relation.journalWebOfScienceCategory | Medicine, Research & Experimental | - |
dc.subject.keywordAuthor | Coronavirus | - |
dc.subject.keywordAuthor | COVID-19 | - |
dc.subject.keywordAuthor | SARS-CoV-2 | - |
dc.subject.keywordAuthor | Vaccine | - |
dc.subject.keywordAuthor | Effectiveness | - |
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