Effect of Stenting Strategy on the Outcome in Patients with Non-Left Main Bifurcation Lesionsopen access
- Authors
- Lim, Yongwhan; Kim, Min Chul; Ahn, Youngkeun; Sim, Doo Sun; Hong, Young Joon; Kim, Ju Han; Jeong, Myung Ho; Gwon, Hyeon-Cheol; Kim, Hyo-Soo; Rha, Seung Woon; Yoon, Jung Han; Jang, Yangsoo; Tahk, Seung-Jea; Seung, Ki Bae
- Issue Date
- 10월-2022
- Publisher
- MDPI
- Keywords
- elective two stent; Bifurcation; percutaneous coronary intervention; non-left main bifurcation; provisional one-stent
- Citation
- JOURNAL OF CLINICAL MEDICINE, v.11, no.19
- Indexed
- SCIE
SCOPUS
- Journal Title
- JOURNAL OF CLINICAL MEDICINE
- Volume
- 11
- Number
- 19
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/145493
- DOI
- 10.3390/jcm11195658
- ISSN
- 2077-0383
- Abstract
- Previous studies have not compared outcomes between different percutaneous coronary intervention (PCI) strategies and lesion locations in non-left main (LM) bifurcation lesions. We enrolled 2044 patients from a multicenter registry with an LAD bifurcation lesion (n = 1551) or non-LAD bifurcation lesion (n = 493). The primary outcome was target lesion failure (TLF), a composite of cardiac death, myocardial infarction, and target lesion revascularization (TLR). During a median follow-up period of 38 months, non-LAD bifurcation lesions treated with the two-stent strategy, compared with the one-stent strategy, were associated with more frequent TLF (20.7% vs. 6.3%, p < 0.01), TLR (16.7% vs. 4.7%, p < 0.01), and target vessel revascularization (TVR; 18.2% vs. 6.3%, p < 0.01). There was no significant difference in outcome among LAD bifurcation lesions treated with different PCI strategies. The two-stent strategy was associated with a higher risk of TLF (adjusted HR 4.34, CI 1.93-9.76, p < 0.01), TLR (adjusted HR 4.30, CI 1.64-11.27, p < 0.01), and TVR (adjusted HR 5.07, CI 1.69-9.74, p < 0.01) in the non-LAD bifurcation lesions. The planned one-stent strategy is preferable to the two-stent strategy for the treatment of non-LAD bifurcation lesions.
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Collections - Graduate School > Department of Biomedical Sciences > 1. Journal Articles
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