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SIWV tetrapeptide and ROS-responsive prodrug conjugate for advanced glioblastoma therapy
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Park, Yoon Kyung | - |
| dc.contributor.author | Jangili, Paramesh | - |
| dc.contributor.author | Zi, Soyu | - |
| dc.contributor.author | Kang, Rae Hyung | - |
| dc.contributor.author | Kim, Dokyoung | - |
| dc.contributor.author | Kim, Jong Seung | - |
| dc.date.accessioned | 2022-11-18T06:41:03Z | - |
| dc.date.available | 2022-11-18T06:41:03Z | - |
| dc.date.created | 2022-11-17 | - |
| dc.date.issued | 2022-09-29 | - |
| dc.identifier.issn | 1359-7345 | - |
| dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/145728 | - |
| dc.description.abstract | A new conjugate formulation, SIWV-PB-SN, based on glioblastoma (GBM)-homing SIWV tetrapeptide and an ROS-responsive prodrug is reported. SIWV-PB-SN selectively penetrates the GBM cells and releases anti-GBM drug (SN-38) via ROS-induced linker cleavage. This study presents a new insight for a more advanced therapeutic approach to overcoming GBM. | - |
| dc.language | English | - |
| dc.language.iso | en | - |
| dc.publisher | ROYAL SOC CHEMISTRY | - |
| dc.title | SIWV tetrapeptide and ROS-responsive prodrug conjugate for advanced glioblastoma therapy | - |
| dc.type | Article | - |
| dc.contributor.affiliatedAuthor | Kim, Jong Seung | - |
| dc.identifier.doi | 10.1039/d2cc03777g | - |
| dc.identifier.scopusid | 2-s2.0-85139240733 | - |
| dc.identifier.wosid | 000851563900001 | - |
| dc.identifier.bibliographicCitation | CHEMICAL COMMUNICATIONS, v.58, no.78, pp.10941 - 10944 | - |
| dc.relation.isPartOf | CHEMICAL COMMUNICATIONS | - |
| dc.citation.title | CHEMICAL COMMUNICATIONS | - |
| dc.citation.volume | 58 | - |
| dc.citation.number | 78 | - |
| dc.citation.startPage | 10941 | - |
| dc.citation.endPage | 10944 | - |
| dc.type.rims | ART | - |
| dc.type.docType | Article | - |
| dc.description.journalClass | 1 | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
| dc.relation.journalResearchArea | Chemistry | - |
| dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
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