Relative Effectiveness of COVID-19 Vaccination in Healthcare Workers: 3-Dose Versus 2-Dose Vaccination
DC Field | Value | Language |
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dc.contributor.author | Kim, S.R. | - |
dc.contributor.author | Kang, H.J. | - |
dc.contributor.author | Jeong, H.R. | - |
dc.contributor.author | Jang, S.Y. | - |
dc.contributor.author | Lee, J.E. | - |
dc.contributor.author | Kim, D.E. | - |
dc.contributor.author | Lee, H.R. | - |
dc.contributor.author | Cho, M.H. | - |
dc.contributor.author | Noh, J.Y. | - |
dc.contributor.author | Cheong, H.J. | - |
dc.contributor.author | Kim, W.J. | - |
dc.contributor.author | Song, J.Y. | - |
dc.date.accessioned | 2022-11-19T20:40:55Z | - |
dc.date.available | 2022-11-19T20:40:55Z | - |
dc.date.created | 2022-11-18 | - |
dc.date.issued | 2022 | - |
dc.identifier.issn | 1011-8934 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/146003 | - |
dc.description.abstract | The omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is known to have high infectivity and is more likely to evade vaccine immunity. However, booster vaccination is expected to strengthen cross-reactive immunity, thereby increasing the vaccine effectiveness (VE). This study aimed to evaluate the relative VE of the 3-dose (booster) vaccination compared with the 2-dose primary series vaccination in healthcare workers during omicron variant-dominant periods. During the omicron-dominant period from February 1, 2022 to February 28, 2022, a 1:1 matched case-control study was conducted. Healthcare workers with positive SARS-CoV-2 test results were classified as positive cases, whereas those with negative results served as controls. Compared with the 2-dose primary series vaccination, booster vaccination with mRNA vaccine showed moderate VE (53.1%). However, in multivariate analysis including the time elapsed after vaccination, the significant VE disappeared, reflecting the impact of recent vaccination rather than the third dose itself. © 2022 The Korean Academy of Medical Sciences. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | Korean Academy of Medical Science | - |
dc.title | Relative Effectiveness of COVID-19 Vaccination in Healthcare Workers: 3-Dose Versus 2-Dose Vaccination | - |
dc.title.alternative | Relative Effectiveness of COVID-19 Vaccination in Healthcare Workers: 3-Dose Versus 2-Dose Vaccination | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Noh, J.Y. | - |
dc.contributor.affiliatedAuthor | Song, J.Y. | - |
dc.identifier.doi | 10.3346/jkms.2022.37.e267 | - |
dc.identifier.scopusid | 2-s2.0-85137247637 | - |
dc.identifier.bibliographicCitation | Journal of Korean Medical Science, v.37, no.35, pp.1 - 5 | - |
dc.relation.isPartOf | Journal of Korean Medical Science | - |
dc.citation.title | Journal of Korean Medical Science | - |
dc.citation.volume | 37 | - |
dc.citation.number | 35 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 5 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002873892 | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.subject.keywordAuthor | Covid-19 | - |
dc.subject.keywordAuthor | Healthcare worker | - |
dc.subject.keywordAuthor | Sars-cov-2 | - |
dc.subject.keywordAuthor | Vaccine effectiveness | - |
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