Imaging finding and analysis of brain lymphoma in contrast-enhanced fluid attenuated inversion recovery sequence
DC Field | Value | Language |
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dc.contributor.author | Chul, Lee Y. | - |
dc.contributor.author | Suh, S. | - |
dc.contributor.author | Ryoo, I. | - |
dc.contributor.author | Jung, H. | - |
dc.contributor.author | Joo, L. | - |
dc.date.accessioned | 2022-11-19T23:41:14Z | - |
dc.date.available | 2022-11-19T23:41:14Z | - |
dc.date.created | 2022-11-18 | - |
dc.date.issued | 2022 | - |
dc.identifier.issn | 0720-048X | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/146034 | - |
dc.description.abstract | Objective: The purpose of this retrospective study was to report and analyze the image findings of contrast-enhanced fluid-attenuated inversion recovery (CE-FLAIR) sequence of lymphoma in the brain. Material and Methods: Thirty-two immunocompetent patients with biopsy-proven diffuse large B-cell type lymphoma in the brain were evaluated with pre-treatment MRI examinations from August 2014 to April 2020. As stereotactic studies on the day of biopsy, FLAIR and T1-weighted axial images were acquired in 2 mm thickness, before and after administrating gadolinium-based contrast agents, with 3.0 Tesla MR machines. Respective subtraction images were also obtained for both CE-FLAIR and contrast-enhanced T1-wieghted image (CE-T1WI) sequences. The imaging findings, especially the enhancement pattern on CE-FLAIR sequence, were analyzed qualitatively and quantitatively, using semi-automatic segmentation. Results: On CE-FLAIR images, brain lymphomas were poorly enhanced, while showing peripheral rim enhancement (54 of 58 lesions, 93.1 %) and central enhancing foci (40 of 58 lesions, 69.0 %). Seventy percent of central enhancing foci were correlated to areas with low signal intensity on CE-T1WI. In quantitative analysis, the mean signal intensity of CE-T1WI subtraction was 490.44 and that of FLAIR subtraction was 206.13. The standard deviation of all signal intensity values in CE-T1WI subtraction sequence was 143.45, while that of CE-FLAIR subtraction sequence was 118.41. Conclusion: On CE-FLAIR, brain lymphomas showed relatively poor and homogeneous enhancement, when compared to CE-T1WI. Most brain lymphomas displayed peripheral rim enhancement and central enhancing foci. © 2022 Elsevier B.V. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | Elsevier Ireland Ltd | - |
dc.title | Imaging finding and analysis of brain lymphoma in contrast-enhanced fluid attenuated inversion recovery sequence | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Ryoo, I. | - |
dc.contributor.affiliatedAuthor | Jung, H. | - |
dc.identifier.doi | 10.1016/j.ejrad.2022.110490 | - |
dc.identifier.scopusid | 2-s2.0-85136580739 | - |
dc.identifier.bibliographicCitation | European Journal of Radiology, v.155 | - |
dc.relation.isPartOf | European Journal of Radiology | - |
dc.citation.title | European Journal of Radiology | - |
dc.citation.volume | 155 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordAuthor | Brain lymphoma | - |
dc.subject.keywordAuthor | CE-FLAIR | - |
dc.subject.keywordAuthor | CNS lymphoma | - |
dc.subject.keywordAuthor | Contrast-enhanced fluid attenuated inversion recovery | - |
dc.subject.keywordAuthor | Semi-automatic segmentation | - |
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