Assessment of coronary spasms with transluminal attenuation gradient in coronary computed tomography angiography
DC Field | Value | Language |
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dc.contributor.author | Park, Jae Yang | - |
dc.contributor.author | Kang, Eun-Ju | - |
dc.contributor.author | Kim, Moo Hyun | - |
dc.contributor.author | Yong, Hwan Seok | - |
dc.contributor.author | Rha, Seung-Woon | - |
dc.date.accessioned | 2022-12-09T17:42:43Z | - |
dc.date.available | 2022-12-09T17:42:43Z | - |
dc.date.created | 2022-12-08 | - |
dc.date.issued | 2022-07-08 | - |
dc.identifier.issn | 1932-6203 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/146623 | - |
dc.description.abstract | Purpose To evaluate the imaging features of coronary spasm, including transluminal attenuation gradient (TAG) on coronary computed tomography angiography (CCTA), in patients with vasospastic angina (VA). Methods A total of 43 patients with a high clinical likelihood of VA were included in the study. All the subjects underwent double CCTA acquisition: CCTA without a vasodilator (`baseline CT') and CCTA during continuous intravenous nitrate infusion (`IV nitrate CT'). A catheterized ergonovine provocation test was used to determine true VA patients. Coronary spasm is classified into focal- and diffuse-types according to morphological differences. We measured TAG and contrast enhancement of the proximal ostium (ProxHU) of each coronary artery for both the baseline and IV nitrate CT. Results Twenty-four patients (55.8%) showed positive results of coronary vasospasm on the provocation test. Thirty-eight vessels showed coronary spasms (29.5%): Focal-type in nine vessels (24%), and diffuse-type in 29 (76%). In the baseline CT, LCX showed significantly lower (steeper) TAG in spasm(+) vessels than in spasm(-) vessels, while LAD and RCA showed no significant differences in TAG. The ProxHU of LAD showed significantly lower values in spasm(+) vessels than in spasm(-) vessels, while the other vessels did not show significant differences in ProxHU. For IV nitrate CT, there were no significant differences in either the TAG and ProxHU between spasm(+) and (-) vessels for all the three vessel types. In subgroup analysis for spasm(+) vessels, diffuse spasms showed significantly lower TAG than focal spasms, while the ProxHU did not differ between the two types of spasm. Conclusions A relatively large percentage of coronary spasms present as diffuse type, and the TAG values significantly differed according to the morphological type of the coronary spasm. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | PUBLIC LIBRARY SCIENCE | - |
dc.subject | ARTERY SPASM | - |
dc.subject | CT ANGIOGRAPHY | - |
dc.subject | FLOW RESERVE | - |
dc.subject | ERGONOVINE | - |
dc.subject | DIAGNOSIS | - |
dc.subject | STENOSIS | - |
dc.subject | DIAMETER | - |
dc.title | Assessment of coronary spasms with transluminal attenuation gradient in coronary computed tomography angiography | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Yong, Hwan Seok | - |
dc.identifier.doi | 10.1371/journal.pone.0271189 | - |
dc.identifier.scopusid | 2-s2.0-85133717958 | - |
dc.identifier.wosid | 000844536800131 | - |
dc.identifier.bibliographicCitation | PLOS ONE, v.17, no.7 | - |
dc.relation.isPartOf | PLOS ONE | - |
dc.citation.title | PLOS ONE | - |
dc.citation.volume | 17 | - |
dc.citation.number | 7 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.subject.keywordPlus | ARTERY SPASM | - |
dc.subject.keywordPlus | CT ANGIOGRAPHY | - |
dc.subject.keywordPlus | FLOW RESERVE | - |
dc.subject.keywordPlus | ERGONOVINE | - |
dc.subject.keywordPlus | DIAGNOSIS | - |
dc.subject.keywordPlus | STENOSIS | - |
dc.subject.keywordPlus | DIAMETER | - |
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