The thalamocortical inhibitory network controls human conscious perceptionopen access
- Authors
- Seo, J.; Kim, D.-J.; Choi, S.-H.; Kim, H.; Min, B.-K.
- Issue Date
- 2022
- Publisher
- Academic Press Inc.
- Keywords
- Conscious perception; Default-mode network; Illusory colour; Thalamic reticular nucleus; Thalamocortical inhibitory network
- Citation
- NeuroImage, v.264
- Indexed
- SCIE
SCOPUS
- Journal Title
- NeuroImage
- Volume
- 264
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/146973
- DOI
- 10.1016/j.neuroimage.2022.119748
- ISSN
- 1053-8119
- Abstract
- Although conscious perception is a fundamental cognitive function, its neural correlates remain unclear. It remains debatable whether thalamocortical interactions play a decisive role in conscious perception. To clarify this, we used functional magnetic resonance imaging (fMRI) where flickering red and green visual cues could be perceived either as a non-fused colour or fused colour. Here we show significantly differentiated fMRI neurodynamics only in higher-order thalamocortical regions, compared with first-order thalamocortical regions. Anticorrelated neurodynamic behaviours were observed between the visual stream network and default-mode network. Its dynamic causal modelling consistently provided compelling evidence for the involvement of higher-order thalamocortical iterative integration during conscious perception of fused colour, while inhibitory control was revealed during the non-fusion condition. Taken together with our recent magnetoencephalography study, our fMRI findings corroborate a thalamocortical inhibitory model for consciousness, where both thalamic inhibitory regulation and integrative signal iterations across higher-order thalamocortical regions are essential for conscious perception. © 2022
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Collections - Graduate School > Department of Brain and Cognitive Engineering > 1. Journal Articles
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