Long‑term outcome of the endoscopic submucosal dissection of early gastric cancer: A comparison between patients with and without liver cirrhosis
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, S.H. | - |
dc.contributor.author | Joo, M.K. | - |
dc.contributor.author | Yoo, A.-Y. | - |
dc.contributor.author | Kim, S.M. | - |
dc.contributor.author | Kim, W.S. | - |
dc.contributor.author | Lee, B.J. | - |
dc.contributor.author | Park, J.J. | - |
dc.contributor.author | Chun, H.J. | - |
dc.contributor.author | Lee, S.W. | - |
dc.date.accessioned | 2022-12-11T18:41:27Z | - |
dc.date.available | 2022-12-11T18:41:27Z | - |
dc.date.created | 2022-12-08 | - |
dc.date.issued | 2022-11 | - |
dc.identifier.issn | 1792-1074 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/147065 | - |
dc.description.abstract | Gastric cancer (GC) and liver cirrhosis (LC) have high incidence rates, particularly in Eastern Asia; however, the long‑term clinical outcomes or recurrence of GC following endoscopic submucosal dissection (ESD) in patients with comorbid LC remain unclear. The present study aimed to compare the long‑term efficacy and safety of ESD in patients with GC, with and without LC. Patients with early GC (EGC) who had underlying LC and underwent endoscopic treat‑ ment (LC‑EGC group) were enrolled in the present study. In addition, patients with EGC without LC (non‑LC‑EGC group) were matched at a ratio of 1:3 via propensity score matching. The clinical outcomes and histopathological data of both groups were analyzed. No significant differences were observed in procedure type, complications [intrapro‑ cedural bleeding (11.8%) and perforation (0.0%)], en bloc resection rate (94.1%) and complete resection rate (100%) between the two groups. Multivariate Cox regression analysis demonstrated that procedure time was significantly associ‑ ated with procedure‑associated bleeding [adjusted hazard ratio (HR), 1.017; 95% confidence interval (CI), 1.001‑1.032; P=0.033]. Furthermore, LC was significantly associated with cancer recurrence (adjusted HR, 5.482; 95% CI, 1.102‑27.279; P=0.038). Taken together, the results of the present study suggest that endoscopic resection of EGC in patients with LC is an effective and safe treatment method. However, further studies are required to assess recurrence. © 2022 Spandidos Publications. All rights reserved. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | Spandidos Publications | - |
dc.title | Long‑term outcome of the endoscopic submucosal dissection of early gastric cancer: A comparison between patients with and without liver cirrhosis | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, S.H. | - |
dc.identifier.doi | 10.3892/ol.2022.13524 | - |
dc.identifier.scopusid | 2-s2.0-85140270326 | - |
dc.identifier.wosid | 000891420200001 | - |
dc.identifier.bibliographicCitation | Oncology Letters, v.24, no.5 | - |
dc.relation.isPartOf | Oncology Letters | - |
dc.citation.title | Oncology Letters | - |
dc.citation.volume | 24 | - |
dc.citation.number | 5 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.isOpenAccess | Y | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Oncology | - |
dc.relation.journalWebOfScienceCategory | Oncology | - |
dc.subject.keywordPlus | DISEASES | - |
dc.subject.keywordPlus | KOREA | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordAuthor | comorbidity | - |
dc.subject.keywordAuthor | endoscopic resection | - |
dc.subject.keywordAuthor | gastric cancer | - |
dc.subject.keywordAuthor | prognosis | - |
dc.subject.keywordAuthor | treatment | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
145 Anam-ro, Seongbuk-gu, Seoul, 02841, Korea+82-2-3290-2963
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.