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Impact of waist circumference on the risk of vertebral fracture: A nationwide cohort study in South Korea

Authors
Kim, WonsockNam, Ga EunHan, KyungdoJung, Jin-HyungLee, JongkyungPark, Chan MiKim, Yang-HyunKim, Jung-HwanKim, Seon MeePark, Yong GyuCho, Kyung Hwan
Issue Date
4월-2021
Publisher
ELSEVIER SCIENCE INC
Keywords
Vertebral fracture; Obesity; Abdominal obesity; Waist circumference
Citation
BONE, v.145
Indexed
SCIE
SCOPUS
Journal Title
BONE
Volume
145
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/49453
DOI
10.1016/j.bone.2021.115870
ISSN
8756-3282
Abstract
Evidence on the association between abdominal obesity and vertebral fracture (VF) risk is limited. We examined the association of waist circumference (WC) and abdominal obesity with VF risk in 352,095 South Korean participants aged 75.0 cm (HR: 0.81, 95% CI: 0.75-0.88) and increased in those with WC 85.0-89.9 cm (HR: 1.12, 95% CI: 1.02-1.22), 90.0-94.9 cm (HR: 1.19, 95% CI: 1.08-1.32), and 95.0 cm (HR: 1.27, 95% CI: 1.12-1.43) compared with those with WC 80.0-84.9 cm. This association persisted after stratification by age in women. WC and abdominal obesity were positively associated with VF risk in women, and abdominal obesity was associated with VF risk even in men. The consideration of WC and controlling abdominal obesity may be helpful in reducing future VF risk.
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