Diterpenoids and Diacetylenes from the Roots of Aralia cordata with Inhibitory Effects on Nitric Oxide Production
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Jun Gu | - |
dc.contributor.author | Lee, Jin Woo | - |
dc.contributor.author | Thi Phuong Linh Le | - |
dc.contributor.author | Han, Jae Sang | - |
dc.contributor.author | Kwon, Haeun | - |
dc.contributor.author | Lee, Dongho | - |
dc.contributor.author | Hong, Jin Tae | - |
dc.contributor.author | Kim, Youngsoo | - |
dc.contributor.author | Lee, Mi Kyeong | - |
dc.contributor.author | Hwang, Bang Yeon | - |
dc.date.accessioned | 2021-08-30T02:55:55Z | - |
dc.date.available | 2021-08-30T02:55:55Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2021-02-26 | - |
dc.identifier.issn | 0163-3864 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/49544 | - |
dc.description.abstract | Bioactivity-guided isolation of a MeOH extract of Aralia cordata led to the isolation of four new ent-pimarane diterpenoids (1-4) and a diacetylene (5) together with 21 known compounds (6-26). Their structures were established based on the interpretation of one- and two-dimensional NMR and HRESIMS data. The absolute configurations of the new isolates were determined by electronic circular dichroism data analysis, single crystal X-ray diffraction, and Mosher's esterification method. All compounds exhibited inhibitory effects on lipopolysaccharide-induced nitric oxide production in RAW 264.7 macrophages with IC50 values ranging from 1.1 to 69.4 mu M. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.title | Diterpenoids and Diacetylenes from the Roots of Aralia cordata with Inhibitory Effects on Nitric Oxide Production | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Dongho | - |
dc.identifier.doi | 10.1021/acs.jnatprod.0c00842 | - |
dc.identifier.scopusid | 2-s2.0-85100156392 | - |
dc.identifier.wosid | 000624549800006 | - |
dc.identifier.bibliographicCitation | JOURNAL OF NATURAL PRODUCTS, v.84, no.2, pp.230 - 238 | - |
dc.relation.isPartOf | JOURNAL OF NATURAL PRODUCTS | - |
dc.citation.title | JOURNAL OF NATURAL PRODUCTS | - |
dc.citation.volume | 84 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 230 | - |
dc.citation.endPage | 238 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Plant Sciences | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalWebOfScienceCategory | Plant Sciences | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Medicinal | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.