F-18-labelled BODIPY dye as a dual imaging agent: Radiofluorination and applications in PET and optical imaging
DC Field | Value | Language |
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dc.contributor.author | Kwon, Young-Do | - |
dc.contributor.author | Byun, Youngjoo | - |
dc.contributor.author | Kim, Hee-Kwon | - |
dc.date.accessioned | 2021-08-30T03:32:55Z | - |
dc.date.available | 2021-08-30T03:32:55Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2021-02 | - |
dc.identifier.issn | 0969-8051 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/49705 | - |
dc.description.abstract | Dual Positron emission tomography (PET)/optical imaging techniques have captured scientific interest for clinical applications due to their potential as an effective tool for visualizing in vivo information such as disease processes. 4,4'-Difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY) dye has been considered an ideal platform strategy to achieve dual PET/optical imaging due to its photochemical nature and chemical structure. Various radiofluorination methods to prepare [F-18]BODIPY dye have been developed and established, ranging from nucle-ophilic substitution reactions to isotope exchange reactions. In addition, F-18-labelled BODIPY dyes for biologically important targets have been used for in vivo and ex vivo studies. These studies proved the practicality of [F-18] BODIPY dyes as a hybrid PET/optical imaging probe. In this review, recent advances in the synthesis and biological evaluation of F-18-labelled BODIPY dyes are described. (C) 2020 Elsevier Inc. All rights reserved. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE INC | - |
dc.title | F-18-labelled BODIPY dye as a dual imaging agent: Radiofluorination and applications in PET and optical imaging | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Byun, Youngjoo | - |
dc.identifier.doi | 10.1016/j.nucmedbio.2020.11.004 | - |
dc.identifier.scopusid | 2-s2.0-85097133897 | - |
dc.identifier.wosid | 000620245100004 | - |
dc.identifier.bibliographicCitation | NUCLEAR MEDICINE AND BIOLOGY, v.93, pp.22 - 36 | - |
dc.relation.isPartOf | NUCLEAR MEDICINE AND BIOLOGY | - |
dc.citation.title | NUCLEAR MEDICINE AND BIOLOGY | - |
dc.citation.volume | 93 | - |
dc.citation.startPage | 22 | - |
dc.citation.endPage | 36 | - |
dc.type.rims | ART | - |
dc.type.docType | Review | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.relation.journalWebOfScienceCategory | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.subject.keywordAuthor | BODIPY dyes | - |
dc.subject.keywordAuthor | Molecular imaging | - |
dc.subject.keywordAuthor | PET | - |
dc.subject.keywordAuthor | Fluorescent | - |
dc.subject.keywordAuthor | Radiofluorination | - |
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