Extracellular RNA: Emerging roles in cancer cell communication and biomarkers
- Authors
- Kim, Seokho; Jeon, Ok Hee; Jeon, Young-Jun
- Issue Date
- 28-12월-2020
- Publisher
- ELSEVIER IRELAND LTD
- Citation
- CANCER LETTERS, v.495, pp.33 - 40
- Indexed
- SCIE
SCOPUS
- Journal Title
- CANCER LETTERS
- Volume
- 495
- Start Page
- 33
- End Page
- 40
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/50760
- DOI
- 10.1016/j.canlet.2020.09.002
- ISSN
- 0304-3835
- Abstract
- Extracellular RNAs (exRNAs) are a type of RNA molecules that present in various biological fluids. exRNAs are heterogenous populations including small (e.g., miRNA) and long non-coding RNAs and coding RNAs (e.g., mRNA). They can exist in a free form or associate with carriers range from lipoand ribo-proteins to extracellular vesicles such as exosomes in the extracellular fluids. exRNAs participate in cell-to-cell communication to regulate a broad array of physiological and pathological processes. exRNAs have been widely studied as a biomarker for cancer and other diseases. In this review, we will discuss the sorts of exRNAs with potential carriers as well as their roles in cancer.
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Collections - Graduate School > Department of Biomedical Sciences > 1. Journal Articles
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