Highly Efficient Aggregation-Induced Red-Emissive Organic Thermally Activated Delayed Fluorescence Materials with Prolonged Fluorescence Lifetime for Time-Resolved Luminescence Bioimaging
- Authors
- Qi, Sujie; Kim, Sangin; Nguyen, Van-Nghia; Kim, Youngmee; Niu, Guangle; Kim, Gyoungmi; Kim, Sung-Jin; Park, Sungnam; Yoon, Juyoung
- Issue Date
- 18-11월-2020
- Publisher
- AMER CHEMICAL SOC
- Keywords
- thermally activated delayed fluorescence (TADF); aggregation-induced emission; red emission; fluorescence imaging; time-resolved luminescence imaging
- Citation
- ACS APPLIED MATERIALS & INTERFACES, v.12, no.46, pp.51293 - 51301
- Indexed
- SCIE
SCOPUS
- Journal Title
- ACS APPLIED MATERIALS & INTERFACES
- Volume
- 12
- Number
- 46
- Start Page
- 51293
- End Page
- 51301
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/51482
- DOI
- 10.1021/acsami.0c15936
- ISSN
- 1944-8244
- Abstract
- Organic thermally activated delayed fluorescence (TADF) materials are emerging as potential candidates for time-resolved fluorescence imaging in biological systems. However, the development of purely organic TADF materials with bright aggregated-state emissions in the red/near-infrared (NIR) region remains challenging. Here, we report three donor-acceptor-type TADF molecules as promising candidates for time-resolved fluorescence imaging, which are engineered by direct connection of electron-donating moieties (phenoxazine or phenothiazine) and an electron-acceptor 1,8-naphthalimide (NI). Theoretically and experimentally, we elucidate that three TADF materials possessed remarkably small Delta E-ST to promote the occurrence of reverse intersystem crossing (RISC). Moreover, they all exhibit aggregation-induced red emissions and long delayed fluorescence lifetimes without the influence of molecular oxygen. More importantly, these long-lived and biocompatible TADF materials, especially the phenoxazine-substituted NI fluorophores, show great potential for high-contrast fluorescence lifetime imaging in living cells. This study provides further a molecular design strategy for purely organic TADF materials and expands the versatile biological application of long-lived fluorescence research in time-resolved luminescence imaging.
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