Atroposelective Total Syntheses of Naphthylisoquinoline Alkaloids with (P)-Configuration
DC Field | Value | Language |
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dc.contributor.author | Jo, Young-In | - |
dc.contributor.author | Lee, Chun-Young | - |
dc.contributor.author | Cheon, Cheol-Hong | - |
dc.date.accessioned | 2021-08-30T12:13:07Z | - |
dc.date.available | 2021-08-30T12:13:07Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2020-10-02 | - |
dc.identifier.issn | 0022-3263 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/52496 | - |
dc.description.abstract | Asymmetric total syntheses of naphthylisoquinoline alkaloids with a (P)-configuration are described. An atroposelective Suzuki-Miyaura reaction between naphthyl pinacol boronate and an aryl iodide bearing an (S)-2-(N-acetylamino)propyl group at the ortho-position using Pd(OAc)(2) in the presence of SPhos and Ba(OH)(2) provided the (P)-selective biaryl product as the major product without any external chiral sources. This biaryl product was converted into naphthylisoquinoline alkaloids with a (P)-configuration via stereoselective construction of the isoquinoline framework with the appropriate oxidation state and stereochemistry. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.subject | CHIRAL NATURAL-PRODUCTS | - |
dc.subject | STEREOSELECTIVE-SYNTHESIS | - |
dc.subject | ANCISTROTANZANINE-B | - |
dc.subject | KORUPENSAMINES | - |
dc.subject | REAGENTS | - |
dc.subject | LIGANDS | - |
dc.title | Atroposelective Total Syntheses of Naphthylisoquinoline Alkaloids with (P)-Configuration | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Cheon, Cheol-Hong | - |
dc.identifier.doi | 10.1021/acs.joc.0c01661 | - |
dc.identifier.scopusid | 2-s2.0-85095406997 | - |
dc.identifier.wosid | 000577156600067 | - |
dc.identifier.bibliographicCitation | JOURNAL OF ORGANIC CHEMISTRY, v.85, no.19, pp.12770 - 12776 | - |
dc.relation.isPartOf | JOURNAL OF ORGANIC CHEMISTRY | - |
dc.citation.title | JOURNAL OF ORGANIC CHEMISTRY | - |
dc.citation.volume | 85 | - |
dc.citation.number | 19 | - |
dc.citation.startPage | 12770 | - |
dc.citation.endPage | 12776 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Organic | - |
dc.subject.keywordPlus | CHIRAL NATURAL-PRODUCTS | - |
dc.subject.keywordPlus | STEREOSELECTIVE-SYNTHESIS | - |
dc.subject.keywordPlus | ANCISTROTANZANINE-B | - |
dc.subject.keywordPlus | KORUPENSAMINES | - |
dc.subject.keywordPlus | REAGENTS | - |
dc.subject.keywordPlus | LIGANDS | - |
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