Blood Pressure at 6 Months After Acute Myocardial Infarction and Outcomes at 2 Years: The Perils Associated With Excessively Low Blood Pressures
DC Field | Value | Language |
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dc.contributor.author | Song, Pil Sang | - |
dc.contributor.author | Lee, Seung Hun | - |
dc.contributor.author | Jeon, Ki-Hyun | - |
dc.contributor.author | Hahn, Joo-Yong | - |
dc.contributor.author | Hur, Seung-Ho | - |
dc.contributor.author | Rha, Seung-Woon | - |
dc.contributor.author | Yoon, Chang-Hwan | - |
dc.contributor.author | Jeong, Myung Ho | - |
dc.contributor.author | Jeong, Jin-Ok | - |
dc.contributor.author | Seong, In-Whan | - |
dc.contributor.author | Song, Young Bin | - |
dc.contributor.author | Gwon, Hyeon-Cheol | - |
dc.date.accessioned | 2021-08-30T12:55:06Z | - |
dc.date.available | 2021-08-30T12:55:06Z | - |
dc.date.created | 2021-06-19 | - |
dc.date.issued | 2020-10 | - |
dc.identifier.issn | 0828-282X | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/52600 | - |
dc.description.abstract | Background: This study aimed to determine the association between achieved blood pressure at 6-month follow-up and cardiovascular outcomes at 2 years in patients treated with [3-blockers and reninangiotensin-aldosterone blockers after acute myocardial infarction (AMI). Methods: We analyzed data from 5503 patients enrolled in the national AMI registry. Patients with myocardial reinfarction (MrI), rehospitalization for heart failure (rHHF), or stroke before 6-month follow-up were excluded. Achieved blood pressures were categorized into 10-mm Hg increments. The primary outcome was all-cause death. The secondary outcome was a composite of all-cause death, MrI, and rHHF. Hazard ratios (HRs) were estimated with multivariable-adjusted Cox hazards models using 125to 134-mm Hg systolic blood pressure (SBP) and 75to 84-mm Hg diastolic blood pressure (DBP) subgroups as reference. Results: After a median follow-up of 2.1 years, SBP < 115 mm Hg was associated with increased risks for all-cause death (adjusted HR: 2.202 [1.158-4.188]) and for a composite outcome (HR: 1.682 [1.075-2.630]). Likewise, DBP < 75 mm Hg tended to be associated with an increase in all-cause death (HR: 2.078 [0.998-4.327] for DBP of 65 to 74 mm Hg; HR: 2.610 [1.256-5.423] for DBP < 65 mm Hg). Even in patients <75 years, the risk of a composite outcome was increased for DBP < 65 mm Hg (HR: 2.492 [1.401-4.434]). Conclusions: Low blood pressure achieved with beta-blocker and renin-angiotensin-aldosterone blocker at 6 months was associated with an increased risk of all-cause mortality independently of confounding factors in patients with AMI. This finding suggests that caution should be taken for patients with AMI who use blood-pressure-lowering treatments. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE INC | - |
dc.subject | HYPERTENSIVE PATIENTS | - |
dc.subject | MORTALITY | - |
dc.subject | GUIDELINES | - |
dc.subject | COHORT | - |
dc.title | Blood Pressure at 6 Months After Acute Myocardial Infarction and Outcomes at 2 Years: The Perils Associated With Excessively Low Blood Pressures | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Rha, Seung-Woon | - |
dc.identifier.doi | 10.1016/j.cjca.2020.01.026 | - |
dc.identifier.scopusid | 2-s2.0-85091892470 | - |
dc.identifier.wosid | 000577617200021 | - |
dc.identifier.bibliographicCitation | CANADIAN JOURNAL OF CARDIOLOGY, v.36, no.10, pp.1641 - 1648 | - |
dc.relation.isPartOf | CANADIAN JOURNAL OF CARDIOLOGY | - |
dc.citation.title | CANADIAN JOURNAL OF CARDIOLOGY | - |
dc.citation.volume | 36 | - |
dc.citation.number | 10 | - |
dc.citation.startPage | 1641 | - |
dc.citation.endPage | 1648 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Cardiac & Cardiovascular Systems | - |
dc.subject.keywordPlus | HYPERTENSIVE PATIENTS | - |
dc.subject.keywordPlus | MORTALITY | - |
dc.subject.keywordPlus | GUIDELINES | - |
dc.subject.keywordPlus | COHORT | - |
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