Supporting data on enhanced reprogramming of human CD34+ hematopoietic stem cells to induced pluripotent stem cells using human placenta-derived cell conditioned medium
DC Field | Value | Language |
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dc.contributor.author | Lee, Seung-Jin | - |
dc.contributor.author | Kim, Ji-Hea | - |
dc.contributor.author | Kang, Ka-Won | - |
dc.contributor.author | Park, Young | - |
dc.contributor.author | Kim, Byung-Soo | - |
dc.date.accessioned | 2021-08-30T13:52:18Z | - |
dc.date.available | 2021-08-30T13:52:18Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2020-10 | - |
dc.identifier.issn | 2352-3409 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/53052 | - |
dc.description.abstract | The data presented herein support "Generation of an induced pluripotent stem cell line KUMCi001-A from CD34+ bone marrow cells of a patient with acute lymphoblastic leukemia using human placenta-derived cell conditioned medium." The supplementary data were as follows. (1) Comparison of reprogramming efficiency of human placenta-derived cell conditioned medium with defined medium (mTeSR(TM) 1) and the generation of induced pluripotent stem cells (iPSCs) from a patient with acute lymphoblastic leukemia (ALL) with significantly higher reprogramming efficiency than that of the defined medium (P <= 0.05). (2) Evaluation of differentiation capability of the generated ALL_iPSCs into hematopoietic stem cells (HSCs) and comparison with normal iPSCs using the colony-forming unit (CFU) assay. ALL_iPSCs manifested all lineages for hematopoiesis in their colonies similar to normal iPSCs. (3) ALL_iPSCs showed a considerably higher number of burst-forming unit-erythroid colonies indicating the presence of more erythroid progenitors than normal iPSCs; this tendency was confirmed in the CFU assay of ALL_CD34+ cells. This has been previously reported as a feature of ALL. Thus, the hematopoietic characteristics of the donor patient with ALL appear to be maintained in our ALL_hiPSC line although the karyotype was normalized during reprogramming. (C) 2020 The Authors. Published by Elsevier Inc. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER | - |
dc.title | Supporting data on enhanced reprogramming of human CD34+ hematopoietic stem cells to induced pluripotent stem cells using human placenta-derived cell conditioned medium | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Byung-Soo | - |
dc.identifier.doi | 10.1016/j.dib.2020.106140 | - |
dc.identifier.wosid | 000583229100102 | - |
dc.identifier.bibliographicCitation | DATA IN BRIEF, v.32 | - |
dc.relation.isPartOf | DATA IN BRIEF | - |
dc.citation.title | DATA IN BRIEF | - |
dc.citation.volume | 32 | - |
dc.type.rims | ART | - |
dc.type.docType | Article; Data Paper | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.subject.keywordAuthor | Reprogramming | - |
dc.subject.keywordAuthor | Human induced pluripotent stem cells | - |
dc.subject.keywordAuthor | Human placenta-derived cell conditioned medium | - |
dc.subject.keywordAuthor | Hematopoietic stem cells | - |
dc.subject.keywordAuthor | Acute lymphoblastic leukemia | - |
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