Thyroid isthmus agenesis and its clinical significance in a large-scale multidetector CT-based study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Seung Kwan | - |
dc.contributor.author | Seo, Hyung Suk | - |
dc.contributor.author | Lee, Young Hen | - |
dc.contributor.author | Son, Gil Soo | - |
dc.contributor.author | Suh, Sang-il | - |
dc.date.accessioned | 2021-08-30T13:53:09Z | - |
dc.date.available | 2021-08-30T13:53:09Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2020-10 | - |
dc.identifier.issn | 0899-7071 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/53061 | - |
dc.description.abstract | Objective: The purpose of this study was to estimate the incidence and clinical significance of thyroid isthmus agenesis based on multi-detector CT imaging in a large-scale study. Methods: Data from 1601 patients who underwent neck multi-detector CT at our institution from January 2015 to March 2016 were included in this retrospective study. The morphology of each patients thyroid gland was evaluated. We classified thyroid isthmus agenesis into two subgroups according to the thickness of the medial margin: clear-cut type ( > 4 mm) or tapering-edge type (<= 4 mm). Associated thyroid pathologies were also evaluated. Results: Thyroid isthmus agenesis was present in 69 patients (41 males, 28 females), and its incidence was 4.77%. Eleven patients (0.76%) had the clear-cut type and 58 patients (4.01%) had the tapering-edge type. Papillary thyroid carcinoma was diagnosed in 4 patients (5.7% of isthmus agenesis patients). A total of 7 patients underwent thyroid function testing during the course of this study; 1 of these patients presented with borderline hyperthyroidism, and the remaining 6 were in a euthyroid state. The clear-cut type showed a statistically significant narrow gap and a high incidence of pyramidal lobes compared to the tapering-edge type. Conclusion: Thyroid isthmus agenesis is not a rare developmental anomaly of the thyroid gland on multi-detector CT. Based on the metastatic pathophysiology of differentiated thyroid cancer, more extended indications for lobectomy are expected in differentiated thyroid cancer patients with thyroid isthmus agenesis. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE INC | - |
dc.subject | PYRAMIDAL LOBE | - |
dc.subject | CANCER | - |
dc.subject | GLAND | - |
dc.subject | HEMIAGENESIS | - |
dc.subject | PREVALENCE | - |
dc.subject | KOREA | - |
dc.subject | RISK | - |
dc.title | Thyroid isthmus agenesis and its clinical significance in a large-scale multidetector CT-based study | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Seo, Hyung Suk | - |
dc.contributor.affiliatedAuthor | Lee, Young Hen | - |
dc.contributor.affiliatedAuthor | Son, Gil Soo | - |
dc.contributor.affiliatedAuthor | Suh, Sang-il | - |
dc.identifier.doi | 10.1016/j.clinimag.2020.04.038 | - |
dc.identifier.scopusid | 2-s2.0-85085258965 | - |
dc.identifier.wosid | 000558676200021 | - |
dc.identifier.bibliographicCitation | CLINICAL IMAGING, v.66, pp.106 - 110 | - |
dc.relation.isPartOf | CLINICAL IMAGING | - |
dc.citation.title | CLINICAL IMAGING | - |
dc.citation.volume | 66 | - |
dc.citation.startPage | 106 | - |
dc.citation.endPage | 110 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.relation.journalWebOfScienceCategory | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.subject.keywordPlus | PYRAMIDAL LOBE | - |
dc.subject.keywordPlus | CANCER | - |
dc.subject.keywordPlus | GLAND | - |
dc.subject.keywordPlus | HEMIAGENESIS | - |
dc.subject.keywordPlus | PREVALENCE | - |
dc.subject.keywordPlus | KOREA | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordAuthor | Thyroid gland | - |
dc.subject.keywordAuthor | Congenital abnormalities | - |
dc.subject.keywordAuthor | Multidetector computed tomography | - |
dc.subject.keywordAuthor | Thyroid diseases | - |
dc.subject.keywordAuthor | Thyroid function tests | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.