Cartilage tissue engineering for craniofacial reconstruction
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Min-Sook | - |
dc.contributor.author | Kim, Hyung-Kyu | - |
dc.contributor.author | Kim, Deok-Woo | - |
dc.date.accessioned | 2021-08-30T16:05:55Z | - |
dc.date.available | 2021-08-30T16:05:55Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2020-09 | - |
dc.identifier.issn | 2234-6163 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/53687 | - |
dc.description.abstract | Severe cartilage defects and congenital anomalies affect millions of people and involve considerable medical expenses. Tissue engineering offers many advantages over conventional treatments, as therapy can be tailored to specific defects using abundant bioengineered resources. This article introduces the basic concepts of cartilage tissue engineering and reviews recent progress in the field, with a focus on craniofacial reconstruction and facial aesthetics. The basic concepts of tissue engineering consist of cells, scaffolds, and stimuli. Generally, the cartilage tissue engineering process includes the following steps: harvesting autologous chondrogenic cells, cell expansion, redifferentiation, in vitro incubation with a scaffold, and transfer to patients. Despite the promising prospects of cartilage tissue engineering, problems and challenges still exist due to certain limitations. The limited proliferation of chondrocytes and their tendency to dedifferentiate necessitate further developments in stem cell technology and chondrocyte molecular biology. Progress should be made in designing fully biocompatible scaffolds with a minimal immune response to regenerate tissue effectively. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | KOREAN SOC PLASTIC & RECONSTRUCTIVE SURGERY | - |
dc.subject | MESENCHYMAL STEM-CELLS | - |
dc.subject | AUTOLOGOUS AURICULAR CHONDROCYTES | - |
dc.subject | HUMAN ARTICULAR CHONDROCYTES | - |
dc.subject | EAR-SHAPED CARTILAGE | - |
dc.subject | IN-VITRO | - |
dc.subject | SODIUM ALGINATE | - |
dc.subject | CHONDROGENIC DIFFERENTIATION | - |
dc.subject | DIRECTED DIFFERENTIATION | - |
dc.subject | MICROTIA CHONDROCYTES | - |
dc.subject | CLINICAL-APPLICATION | - |
dc.title | Cartilage tissue engineering for craniofacial reconstruction | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Deok-Woo | - |
dc.identifier.doi | 10.5999/aps.2020.01095 | - |
dc.identifier.scopusid | 2-s2.0-85091678798 | - |
dc.identifier.wosid | 000574331200003 | - |
dc.identifier.bibliographicCitation | ARCHIVES OF PLASTIC SURGERY-APS, v.47, no.5, pp.392 - 403 | - |
dc.relation.isPartOf | ARCHIVES OF PLASTIC SURGERY-APS | - |
dc.citation.title | ARCHIVES OF PLASTIC SURGERY-APS | - |
dc.citation.volume | 47 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 392 | - |
dc.citation.endPage | 403 | - |
dc.type.rims | ART | - |
dc.type.docType | Review | - |
dc.identifier.kciid | ART002625437 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Surgery | - |
dc.relation.journalWebOfScienceCategory | Surgery | - |
dc.subject.keywordPlus | MESENCHYMAL STEM-CELLS | - |
dc.subject.keywordPlus | AUTOLOGOUS AURICULAR CHONDROCYTES | - |
dc.subject.keywordPlus | HUMAN ARTICULAR CHONDROCYTES | - |
dc.subject.keywordPlus | EAR-SHAPED CARTILAGE | - |
dc.subject.keywordPlus | IN-VITRO | - |
dc.subject.keywordPlus | SODIUM ALGINATE | - |
dc.subject.keywordPlus | CHONDROGENIC DIFFERENTIATION | - |
dc.subject.keywordPlus | DIRECTED DIFFERENTIATION | - |
dc.subject.keywordPlus | MICROTIA CHONDROCYTES | - |
dc.subject.keywordPlus | CLINICAL-APPLICATION | - |
dc.subject.keywordAuthor | Cartilage | - |
dc.subject.keywordAuthor | Tissue | - |
dc.subject.keywordAuthor | Engineering | - |
dc.subject.keywordAuthor | Chondrocyte | - |
dc.subject.keywordAuthor | Stem cell | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.