The prognostic role of preoperative serum albumin/globulin ratio in patients with non-metastatic renal cell carcinoma undergoing partial or radical nephrectomy
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Chung, Jae-Wook | - |
dc.contributor.author | Park, Dong Jin | - |
dc.contributor.author | Chun, So Young | - |
dc.contributor.author | Choi, Seock Hwan | - |
dc.contributor.author | Lee, Jun Nyung | - |
dc.contributor.author | Kim, Bum Soo | - |
dc.contributor.author | Kim, Hyun Tae | - |
dc.contributor.author | Kim, Tae-Hwan | - |
dc.contributor.author | Yoo, Eun Sang | - |
dc.contributor.author | Byun, Seok-Soo | - |
dc.contributor.author | Hwang, Eu Chang | - |
dc.contributor.author | Kang, Seok Ho | - |
dc.contributor.author | Hong, Sung-Hoo | - |
dc.contributor.author | Chung, Jinsoo | - |
dc.contributor.author | Kwak, Cheol | - |
dc.contributor.author | Kim, Yong- June | - |
dc.contributor.author | Ha, Yun-Sok | - |
dc.contributor.author | Kwon, Tae Gyun | - |
dc.date.accessioned | 2021-08-30T19:14:03Z | - |
dc.date.available | 2021-08-30T19:14:03Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2020-07-20 | - |
dc.identifier.issn | 2045-2322 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/54368 | - |
dc.description.abstract | This multi-institutional study sought to clarify the association between the preoperative serum albumin/globulin ratio (AGR) and the prognosis of renal cell carcinoma (RCC) in a large cohort. This study encompassed eight institutions and 2,970 non-metastatic RCC patients who underwent a radical or partial nephrectomy from the Korean RCC (KORCC) database. A low AGR (1,143 patients; 38.5%) was defined as a preoperative AGR of less than 1.47 and a high AGR (1,827 patients; 61.5%) was defined as that 1.47 or greater. In the low AGR group, older age, female gender, the incidence of symptom presentation when diagnosed, diabetes, and hypertension was higher than in the high AGR group. Patients with low AGRs showed more progressive tumor stages with higher Fuhrman nuclear grades (all P-values<0.05). Patients in the low AGR group had a significantly lower overall survival rate (OS) and recurrence-free survival rate (RFS) in the Kaplan-Meier curves (all P-values<0.05). AGR was an independent prognostic factor for predicting the OS and RFS in the multivariate analysis (all P-values<0.05). The preoperative AGR is approachable and economical to use clinically for estimating the prognosis of RCC patients treated with surgery. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | NATURE PUBLISHING GROUP | - |
dc.subject | CORTICOSTEROID-BINDING GLOBULIN | - |
dc.subject | PLASMA PROTEOME DATABASE | - |
dc.subject | PRETREATMENT ALBUMIN | - |
dc.subject | CURATIVE RESECTION | - |
dc.subject | BREAST-CANCER | - |
dc.subject | INFLAMMATION | - |
dc.subject | PROTEINS | - |
dc.subject | SURVIVAL | - |
dc.subject | PATHOPHYSIOLOGY | - |
dc.subject | GUIDELINES | - |
dc.title | The prognostic role of preoperative serum albumin/globulin ratio in patients with non-metastatic renal cell carcinoma undergoing partial or radical nephrectomy | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kang, Seok Ho | - |
dc.identifier.doi | 10.1038/s41598-020-68975-3 | - |
dc.identifier.scopusid | 2-s2.0-85088253144 | - |
dc.identifier.wosid | 000553556900015 | - |
dc.identifier.bibliographicCitation | SCIENTIFIC REPORTS, v.10, no.1 | - |
dc.relation.isPartOf | SCIENTIFIC REPORTS | - |
dc.citation.title | SCIENTIFIC REPORTS | - |
dc.citation.volume | 10 | - |
dc.citation.number | 1 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.subject.keywordPlus | CORTICOSTEROID-BINDING GLOBULIN | - |
dc.subject.keywordPlus | PLASMA PROTEOME DATABASE | - |
dc.subject.keywordPlus | PRETREATMENT ALBUMIN | - |
dc.subject.keywordPlus | CURATIVE RESECTION | - |
dc.subject.keywordPlus | BREAST-CANCER | - |
dc.subject.keywordPlus | INFLAMMATION | - |
dc.subject.keywordPlus | PROTEINS | - |
dc.subject.keywordPlus | SURVIVAL | - |
dc.subject.keywordPlus | PATHOPHYSIOLOGY | - |
dc.subject.keywordPlus | GUIDELINES | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.