Asymmetric Total Syntheses of Naphthylisoquinoline Alkaloids via Atroposelective Coupling Reaction Using Central Chirality as Atroposelectivity-Controlling Group
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Jo, Young-In | - |
dc.contributor.author | Lee, Chun-Young | - |
dc.contributor.author | Cheon, Cheol-Hong | - |
dc.date.accessioned | 2021-08-30T20:58:37Z | - |
dc.date.available | 2021-08-30T20:58:37Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2020-06-19 | - |
dc.identifier.issn | 1523-7060 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/54991 | - |
dc.description.abstract | We describe the asymmetric total syntheses of naphthylisoquinoline alkaloids. Atroposelective biaryl coupling reaction between naphthyl pinacol boronate and an aryl iodide, bearing (S)-2-aminopropyl group at the ortho-position using the existing central chirality as an atroposelectivity-controlling group, provided the desired biaryl product with high atroposelectivity, without the use of an external chiral source. From the resulting biaryl product, several naphthylisoquinoline alkaloids were prepared via the stereoselective formation of the isoquinoline framework with the appropriate oxidation state and stereochemistry. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.subject | ACETOGENIC ISOQUINOLINE ALKALOIDS | - |
dc.subject | MICHELLAMINES A-C | - |
dc.subject | STEREOSELECTIVE-SYNTHESIS | - |
dc.subject | NATURAL-PRODUCTS | - |
dc.subject | KORUPENSAMINE-A | - |
dc.title | Asymmetric Total Syntheses of Naphthylisoquinoline Alkaloids via Atroposelective Coupling Reaction Using Central Chirality as Atroposelectivity-Controlling Group | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Cheon, Cheol-Hong | - |
dc.identifier.doi | 10.1021/acs.orglett.0c01428 | - |
dc.identifier.scopusid | 2-s2.0-85086234744 | - |
dc.identifier.wosid | 000543669800014 | - |
dc.identifier.bibliographicCitation | ORGANIC LETTERS, v.22, no.12, pp.4653 - 4658 | - |
dc.relation.isPartOf | ORGANIC LETTERS | - |
dc.citation.title | ORGANIC LETTERS | - |
dc.citation.volume | 22 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | 4653 | - |
dc.citation.endPage | 4658 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Organic | - |
dc.subject.keywordPlus | ACETOGENIC ISOQUINOLINE ALKALOIDS | - |
dc.subject.keywordPlus | MICHELLAMINES A-C | - |
dc.subject.keywordPlus | STEREOSELECTIVE-SYNTHESIS | - |
dc.subject.keywordPlus | NATURAL-PRODUCTS | - |
dc.subject.keywordPlus | KORUPENSAMINE-A | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.