Diagnostic Accuracy and Confidence of [18F] FDG PET/MRI in comparison with PET or MRI alone in Head and Neck Cancer
DC Field | Value | Language |
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dc.contributor.author | Park, Jisang | - |
dc.contributor.author | Pak, Kyoungjune | - |
dc.contributor.author | Yun, Tae Jin | - |
dc.contributor.author | Lee, Eun Kyoung | - |
dc.contributor.author | Ryoo, Inseon | - |
dc.contributor.author | Lee, Ji Ye | - |
dc.contributor.author | Hwang, Inpyeong | - |
dc.contributor.author | Yoo, Roh-Eul | - |
dc.contributor.author | Kang, Koung Mi | - |
dc.contributor.author | Choi, Seung Hong | - |
dc.contributor.author | Sohn, Chul-Ho | - |
dc.contributor.author | Cheon, Gi Jeong | - |
dc.contributor.author | Kim, Ji-hoon | - |
dc.date.accessioned | 2021-08-30T21:23:10Z | - |
dc.date.available | 2021-08-30T21:23:10Z | - |
dc.date.created | 2021-06-19 | - |
dc.date.issued | 2020-06-11 | - |
dc.identifier.issn | 2045-2322 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/55029 | - |
dc.description.abstract | The usefulness of PET/MRI in head and neck malignancy has not been fully elucidated. The purpose of our study was to evaluate the diagnostic accuracy and confidence of PET/MRI in comparison with PET or MRI alone. This study included 73 consecutive patients who underwent [18F] FDG PET/MRI in head and neck under the suspicion of malignancy. A neuroradiologist and a nuclear medicine specialist reviewed MRI and PET images, respectively and independently, followed by a consensus review of PET/MRI one month later. For 134 lesions, accuracy and confidence were compared among PET, MRI, and PET/MRI. For lesion base, PET/MRI had a sensitivity of 85.7%, a specificity of 89.1%, a PPV of 89.6%, a negative predictive value of 85.1%, and an accuracy of 87.3%. AUCs of PET/MRI per lesion (0.926) and per patient (0.934) for diagnosing malignancy were higher than PET (0.847 and 0.747, respectively) or MRI (0.836 and 0.798, respectively) alone (P<0.05). More than 80% of the cases (111/134) showed diagnostic concordance between PET and MRI. PPV of PET/MRI was higher in malignant concordant cases (93.2%, 55/59) than in discordant cases (62.5%, 5/8) (p=0.040). Confident scoring rate in malignant concordant cases was higher on PET/MRI (96.6%, 57/59) than on MRI (76.3%, 45/59) (p=0.003). In conclusion, compared with PET or MRI alone, PET/MRI presents better diagnostic performance in accuracy and confidence for diagnosis of malignancy. PET/MRI is useful in patients with head and neck cancer. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | NATURE PUBLISHING GROUP | - |
dc.subject | LYMPH-NODE METASTASES | - |
dc.subject | CLINICAL-USEFULNESS | - |
dc.subject | ORAL-CAVITY | - |
dc.subject | PART 1 | - |
dc.subject | CT | - |
dc.subject | CARCINOMA | - |
dc.subject | IMPACT | - |
dc.subject | TUMORS | - |
dc.title | Diagnostic Accuracy and Confidence of [18F] FDG PET/MRI in comparison with PET or MRI alone in Head and Neck Cancer | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Ryoo, Inseon | - |
dc.identifier.doi | 10.1038/s41598-020-66506-8 | - |
dc.identifier.scopusid | 2-s2.0-85086359877 | - |
dc.identifier.wosid | 000559960100008 | - |
dc.identifier.bibliographicCitation | SCIENTIFIC REPORTS, v.10, no.1 | - |
dc.relation.isPartOf | SCIENTIFIC REPORTS | - |
dc.citation.title | SCIENTIFIC REPORTS | - |
dc.citation.volume | 10 | - |
dc.citation.number | 1 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.subject.keywordPlus | LYMPH-NODE METASTASES | - |
dc.subject.keywordPlus | CLINICAL-USEFULNESS | - |
dc.subject.keywordPlus | ORAL-CAVITY | - |
dc.subject.keywordPlus | PART 1 | - |
dc.subject.keywordPlus | CT | - |
dc.subject.keywordPlus | CARCINOMA | - |
dc.subject.keywordPlus | IMPACT | - |
dc.subject.keywordPlus | TUMORS | - |
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