Neuropsychiatric Traits Associated with Refractory Impulse Control Disorder in Parkinson's Disease
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Choi, Ji-Hyun | - |
dc.contributor.author | Lee, Jee-Young | - |
dc.contributor.author | Jeon, Beomseok | - |
dc.contributor.author | Koh, Seong-Beom | - |
dc.contributor.author | Yoon, Won Tae | - |
dc.contributor.author | Lee, Ho-Won | - |
dc.contributor.author | Kwon, Oh Dae | - |
dc.contributor.author | Kim, Jae Woo | - |
dc.contributor.author | Kim, Jong-Min | - |
dc.contributor.author | Ma, Hyeo-Il | - |
dc.contributor.author | Kim, Hee Tae | - |
dc.contributor.author | Baik, Jong Sam | - |
dc.contributor.author | Cho, Jin Whan | - |
dc.date.accessioned | 2021-08-30T22:15:37Z | - |
dc.date.available | 2021-08-30T22:15:37Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2020-06 | - |
dc.identifier.issn | 1660-2854 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/55470 | - |
dc.description.abstract | Introduction:Impulse control disorder (ICD) in Parkinson's disease (PD) is a critical nonmotor symptom with personality or neuropsychiatric traits contributing to ICD.Objective:This study aimed to identify predictive traits for persistent or paradoxical aggravation of ICD after dopamine agonist substitution therapy for ICD in PD.Methods:We conducted a case-control study using a database of a multicenter intervention trial for ICD in PD. The poor-outcome group was defined by showing paradoxical increases in ICD behaviors after the substitution of dopamine agonists with levodopa. We analyzed the pre-intervention personality traits associated with the poor outcome and also evaluated the risk traits for refractory ICD using a receiver-operating characteristic (ROC) curve analysis.Results:The poor-outcome group showed higher levels of anger expression (p =0.007) and obsessive-compulsive traits (p =0.009) compared with the good-outcome group at the pre-intervention state. In the ROC curve analysis, the Obsessive-Compulsive Inventory showed the highest area under the curve with 80.0% sensitivity and 74.3% specificity in discriminating against the poor-outcome group.Conclusions:Our results suggest that assessment of obsessive compulsiveness may be useful for predicting the refractoriness of ICD behaviors in planning an interventional treatment for ICD in PD. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | KARGER | - |
dc.subject | INTERMITTENT EXPLOSIVE DISORDER | - |
dc.subject | BEHAVIORS | - |
dc.title | Neuropsychiatric Traits Associated with Refractory Impulse Control Disorder in Parkinson's Disease | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Koh, Seong-Beom | - |
dc.identifier.doi | 10.1159/000507447 | - |
dc.identifier.scopusid | 2-s2.0-85086748602 | - |
dc.identifier.wosid | 000544740300002 | - |
dc.identifier.bibliographicCitation | NEURODEGENERATIVE DISEASES, v.19, no.5-6, pp.171 - 177 | - |
dc.relation.isPartOf | NEURODEGENERATIVE DISEASES | - |
dc.citation.title | NEURODEGENERATIVE DISEASES | - |
dc.citation.volume | 19 | - |
dc.citation.number | 5-6 | - |
dc.citation.startPage | 171 | - |
dc.citation.endPage | 177 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalWebOfScienceCategory | Clinical Neurology | - |
dc.relation.journalWebOfScienceCategory | Neurosciences | - |
dc.subject.keywordPlus | INTERMITTENT EXPLOSIVE DISORDER | - |
dc.subject.keywordPlus | BEHAVIORS | - |
dc.subject.keywordAuthor | Impulse control disorder | - |
dc.subject.keywordAuthor | Parkinson&apos | - |
dc.subject.keywordAuthor | s disease | - |
dc.subject.keywordAuthor | Dopamine agonist | - |
dc.subject.keywordAuthor | Neuropsychiatric traits | - |
dc.subject.keywordAuthor | Obsessive compulsiveness | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.