Hemodynamic Features of Microsurgically Identified, Thin-Walled Regions of Unruptured Middle Cerebral Artery Aneurysms Characterized Using Computational Fluid Dynamics
- Authors
- Kim, Jang Hun; Han, Huan; Moon, Young-June; Suh, Sangil; Kwon, Taek-Hyun; Kim, Jong Hyun; Chong, Kyuha; Yoon, Won-Ki
- Issue Date
- 6월-2020
- Publisher
- OXFORD UNIV PRESS INC
- Keywords
- Aneurysm; Computational fluid dynamics; Thin-walled region; Wall shear stress divergence
- Citation
- NEUROSURGERY, v.86, no.6, pp.851 - 859
- Indexed
- SCIE
SCOPUS
- Journal Title
- NEUROSURGERY
- Volume
- 86
- Number
- 6
- Start Page
- 851
- End Page
- 859
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/55488
- DOI
- 10.1093/neuros/nyz311
- ISSN
- 0148-396X
- Abstract
- BACKGROUND: Thin-walled regions (TWRs) of aneurysm surfaces observed in microscopic surgery are thought to be vulnerable areas for growth and rupture of unruptured intracranial aneurysms (UIAs). OBJECTIVE: To identify hemodynamic features of TWRs of aneurysms by using computational fluid dynamics (CFD) analyses of unruptured middle cerebral artery bifurcation (MCAB) aneurysms. METHODS: Nine patients with 11 MCAB aneurysms were enrolled, and their TWRs were identified. CFD analysis was performed using 3 parameters: pressure, wall shear stress (WSS), and WSS divergence (WSSD). Each parameter was evaluated for its correspondence with TWR. RESULTS: Among 11 aneurysms, 15 TWRs were identified. Corresponding matches with CFD parameters (pressure, WSS, and WSSD) were 73.33, 46.67, and 86.67%, respectively. CONCLUSION: WSSD, a hemodynamic parameter that accounts for both magnitude and directionality of WSS, showed the highest correspondence. High WSSD might correspond with TWR of intracranial aneurysms, which are likely high-risk areas for rupture.
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Collections - College of Engineering > Department of Mechanical Engineering > 1. Journal Articles
- College of Medicine > Department of Medical Science > 1. Journal Articles
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