Design of Magnetic-Plasmonic Nanoparticle Assemblies via Interface Engineering of Plasmonic Shells for Targeted Cancer Cell Imaging and Separation
DC Field | Value | Language |
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dc.contributor.author | Kim, Myeong Soo | - |
dc.contributor.author | Park, Bum Chul | - |
dc.contributor.author | Kim, Yu Jin | - |
dc.contributor.author | Lee, Ju Hun | - |
dc.contributor.author | Koo, Thomas Myeongseok | - |
dc.contributor.author | Ko, Min Jun | - |
dc.contributor.author | Kim, Young Keun | - |
dc.date.accessioned | 2021-08-31T01:04:57Z | - |
dc.date.available | 2021-08-31T01:04:57Z | - |
dc.date.created | 2021-06-19 | - |
dc.date.issued | 2020-05 | - |
dc.identifier.issn | 1613-6810 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/56075 | - |
dc.description.abstract | Magnetic-plasmonic nanoparticles have received considerable attention for widespread applications. These nanoparticles (NPs) exhibiting surface-enhanced Raman scattering (SERS) activities are developed due to their potential in bio-sensing applicable in non-destructive and sensitive analysis with target-specific separation. However, it is challenging to synthesize these NPs that simultaneously exhibit low remanence, maximized magnetic content, plasmonic coverage with abundant hotspots, and structural uniformity. Here, a method that involves the conjugation of a magnetic template with gold seeds via chemical binding and seed-mediated growth is proposed, with the objective of obtaining plasmonic nanostructures with abundant hotspots on a magnetic template. To obtain a clean surface for directly functionalizing ligands and enhancing the Raman intensity, an additional growth step of gold (Au) and/or silver (Ag) atoms is proposed after modifying the Raman molecules on the as-prepared magnetic-plasmonic nanoparticles. Importantly, one-sided silver growth occurred in an environment where gold facets are blocked by Raman molecules; otherwise, the gold growth is layer-by-layer. Moreover, simultaneous reduction by gold and silver ions allowed for the formation of a uniform bimetallic layer. The enhancement factor of the nanoparticles with a bimetallic layer is approximately 10(7). The SERS probes functionalized cyclic peptides are employed for targeted cancer-cell imaging and separation. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | WILEY-V C H VERLAG GMBH | - |
dc.subject | ENHANCED RAMAN-SCATTERING | - |
dc.subject | HYDROPHOBIC NANOPARTICLES | - |
dc.subject | RGD PEPTIDES | - |
dc.subject | GOLD | - |
dc.subject | INTEGRIN | - |
dc.subject | GROWTH | - |
dc.subject | NANOSTRUCTURES | - |
dc.subject | MICROSPHERES | - |
dc.subject | LIGAND | - |
dc.subject | CORE | - |
dc.title | Design of Magnetic-Plasmonic Nanoparticle Assemblies via Interface Engineering of Plasmonic Shells for Targeted Cancer Cell Imaging and Separation | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Young Keun | - |
dc.identifier.doi | 10.1002/smll.202001103 | - |
dc.identifier.scopusid | 2-s2.0-85083772317 | - |
dc.identifier.wosid | 000528022000001 | - |
dc.identifier.bibliographicCitation | SMALL, v.16, no.20 | - |
dc.relation.isPartOf | SMALL | - |
dc.citation.title | SMALL | - |
dc.citation.volume | 16 | - |
dc.citation.number | 20 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalResearchArea | Physics | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Physical | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Physics, Applied | - |
dc.relation.journalWebOfScienceCategory | Physics, Condensed Matter | - |
dc.subject.keywordPlus | ENHANCED RAMAN-SCATTERING | - |
dc.subject.keywordPlus | HYDROPHOBIC NANOPARTICLES | - |
dc.subject.keywordPlus | RGD PEPTIDES | - |
dc.subject.keywordPlus | GOLD | - |
dc.subject.keywordPlus | INTEGRIN | - |
dc.subject.keywordPlus | GROWTH | - |
dc.subject.keywordPlus | NANOSTRUCTURES | - |
dc.subject.keywordPlus | MICROSPHERES | - |
dc.subject.keywordPlus | LIGAND | - |
dc.subject.keywordPlus | CORE | - |
dc.subject.keywordAuthor | layer-by-layer growth | - |
dc.subject.keywordAuthor | island growth | - |
dc.subject.keywordAuthor | surface ligands | - |
dc.subject.keywordAuthor | bimetallic layers | - |
dc.subject.keywordAuthor | surface plasmon resonance | - |
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