MORPHOLOGIC FEATURES OF THE RETINAL PIGMENT EPITHELIUM AND ASSOCIATED CHORIORETINAL CHARACTERISTICS IN EYES WITH EARLY AGE-RELATED MACULAR DEGENERATION AND SUBRETINAL DRUSENOID DEPOSITS
DC Field | Value | Language |
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dc.contributor.author | Jang, Sungmin | - |
dc.contributor.author | Park, Seo Yeon | - |
dc.contributor.author | Ahn, So Min | - |
dc.contributor.author | Hwang, Soon-Young | - |
dc.contributor.author | Kim, Seong-Woo | - |
dc.contributor.author | Oh, Jaeryung | - |
dc.contributor.author | Yun, Cheolmin | - |
dc.date.accessioned | 2021-08-31T04:47:47Z | - |
dc.date.available | 2021-08-31T04:47:47Z | - |
dc.date.created | 2021-06-19 | - |
dc.date.issued | 2020-04 | - |
dc.identifier.issn | 0275-004X | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/56773 | - |
dc.description.abstract | Purpose: To investigate the features of the retinal pigment epithelium (RPE) on optical coherence tomography in eyes with early age-related macular degeneration with subretinal drusenoid deposit. Methods: We classified the eyes into three types: nonundulating RPE, undulating RPE, and wedge-shaped RPE. We compared the retinal vessel densities, retinal thickness, and choroidal thickness of a 3-mm-diameter zone. Results: We classified 33, 27, and 20 as nonundulating RPE, undulating RPE, and wedge-shaped RPE eyes, respectively. The vascular densities of the superficial and deep capillary plexus showed differences; nonundulating RPE group (23.93 +/- 2.26% and 23.54 +/- 1.78%), undulating RPE group (22.29 +/- 2.80% and 21.94 +/- 2.42%), and wedge-shaped RPE group (21.93 +/- 2.70% and 20.63 +/- 2.42%, P = 0.010 and P < 0.001). The mean retinal thickness and choroidal thickness were also different, nonundulating RPE group (298.26 +/- 13.81 mu m and 180.08 +/- 55.49 mu m), undulating RPE group (285.29 +/- 21.88 mu m and 148.45 +/- 55.08 mu m), and wedge-shaped RPE group (274.86 +/- 20.62 mu m and 135.75 +/- 39.77 mu m) (P = 0.001 and P = 0.007). Conclusion: Altered features of the RPE on optical coherence tomography may indicate advancement in disease and be part of an overall degeneration process in these eyes. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | - |
dc.subject | OPTICAL COHERENCE TOMOGRAPHY | - |
dc.subject | RETICULAR PSEUDODRUSEN | - |
dc.subject | GEOGRAPHIC ATROPHY | - |
dc.subject | QUANTITATIVE-ANALYSIS | - |
dc.subject | CHOROIDAL THICKNESS | - |
dc.subject | CLINICAL-TRIAL | - |
dc.subject | SYSTEM | - |
dc.subject | RPE | - |
dc.title | MORPHOLOGIC FEATURES OF THE RETINAL PIGMENT EPITHELIUM AND ASSOCIATED CHORIORETINAL CHARACTERISTICS IN EYES WITH EARLY AGE-RELATED MACULAR DEGENERATION AND SUBRETINAL DRUSENOID DEPOSITS | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Seong-Woo | - |
dc.contributor.affiliatedAuthor | Oh, Jaeryung | - |
dc.contributor.affiliatedAuthor | Yun, Cheolmin | - |
dc.identifier.doi | 10.1097/IAE.0000000000002528 | - |
dc.identifier.scopusid | 2-s2.0-85082561072 | - |
dc.identifier.wosid | 000524497800012 | - |
dc.identifier.bibliographicCitation | RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, v.40, no.4, pp.686 - 694 | - |
dc.relation.isPartOf | RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES | - |
dc.citation.title | RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES | - |
dc.citation.volume | 40 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 686 | - |
dc.citation.endPage | 694 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Ophthalmology | - |
dc.relation.journalWebOfScienceCategory | Ophthalmology | - |
dc.subject.keywordPlus | OPTICAL COHERENCE TOMOGRAPHY | - |
dc.subject.keywordPlus | RETICULAR PSEUDODRUSEN | - |
dc.subject.keywordPlus | GEOGRAPHIC ATROPHY | - |
dc.subject.keywordPlus | QUANTITATIVE-ANALYSIS | - |
dc.subject.keywordPlus | CHOROIDAL THICKNESS | - |
dc.subject.keywordPlus | CLINICAL-TRIAL | - |
dc.subject.keywordPlus | SYSTEM | - |
dc.subject.keywordPlus | RPE | - |
dc.subject.keywordAuthor | early age-related macular degeneration | - |
dc.subject.keywordAuthor | optical coherence tomography | - |
dc.subject.keywordAuthor | optical coherence tomography angiography | - |
dc.subject.keywordAuthor | subretinal drusenoid deposits | - |
dc.subject.keywordAuthor | retinal pigment epithelium | - |
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