Elimination of Unreacted Acrylate Double Bonds in the Polymer Networks of Microparticles Synthesized via Flow Lithography
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Moon, Hyun June | - |
dc.contributor.author | Ku, Minhee | - |
dc.contributor.author | Roh, Yoonho | - |
dc.contributor.author | Lee, Hyun Jee | - |
dc.contributor.author | Yang, Jaemoon | - |
dc.contributor.author | Bong, Ki Wan | - |
dc.date.accessioned | 2021-08-31T07:46:47Z | - |
dc.date.available | 2021-08-31T07:46:47Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2020-03-10 | - |
dc.identifier.issn | 0743-7463 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/57304 | - |
dc.description.abstract | Flow lithography (FL), a versatile technique used to synthesize anisotropic multifunctional microparticles, has attracted substantial interest, given that the resulting particles with complex geometries and multilayered biochemical functionalities can be used in a wide variety of applications. However, after this process, there are double bonds remaining from the cross-linkable groups of monomers. The unreacted cross-linkable groups can affect the particles' biochemical properties. Here, we verify that the microparticles produced by FL contain a significant number of unreacted acrylate double bonds (UADBs), which could cause irreversible biochemical changes in the particle and pernicious effects to biological systems. We also confirm that the particles contain a considerable number of UADBs, regardless of the various synthetic (lithographic) conditions that can be used in a typical FL process. We present an effective way to eliminate a substantial amount of UADBs after synthesis by linking biochemically inert poly(ethylene glycol) based on click chemistry. We verify that eliminating UADBs by using this click chemistry approach can efficiently resolve problems, such as the occurrence of random reactions and the cytotoxicity of UADBs. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.subject | POLY(ETHYLENE GLYCOL) | - |
dc.subject | HYDROGEL PARTICLES | - |
dc.subject | THIOL | - |
dc.subject | CELL | - |
dc.subject | PHOTOPOLYMERIZATION | - |
dc.subject | KINETICS | - |
dc.title | Elimination of Unreacted Acrylate Double Bonds in the Polymer Networks of Microparticles Synthesized via Flow Lithography | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Bong, Ki Wan | - |
dc.identifier.doi | 10.1021/acs.langmuir.9b02737 | - |
dc.identifier.scopusid | 2-s2.0-85081887723 | - |
dc.identifier.wosid | 000519337400013 | - |
dc.identifier.bibliographicCitation | LANGMUIR, v.36, no.9, pp.2271 - 2277 | - |
dc.relation.isPartOf | LANGMUIR | - |
dc.citation.title | LANGMUIR | - |
dc.citation.volume | 36 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 2271 | - |
dc.citation.endPage | 2277 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Physical | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
dc.subject.keywordPlus | POLY(ETHYLENE GLYCOL) | - |
dc.subject.keywordPlus | HYDROGEL PARTICLES | - |
dc.subject.keywordPlus | THIOL | - |
dc.subject.keywordPlus | CELL | - |
dc.subject.keywordPlus | PHOTOPOLYMERIZATION | - |
dc.subject.keywordPlus | KINETICS | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.