Randomized Comparison of Everolimus- and Zotarolimus-Eluting Coronary Stents With Biolimus-Eluting Stents in All-Comer Patients
DC Field | Value | Language |
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dc.contributor.author | Youn, Young Jin | - |
dc.contributor.author | Lee, Jun-Won | - |
dc.contributor.author | Ahn, Sung Gyun | - |
dc.contributor.author | Lee, Seung-Hwan | - |
dc.contributor.author | Yoon, Junghan | - |
dc.contributor.author | Park, Keum Soo | - |
dc.contributor.author | Lee, Jin Bae | - |
dc.contributor.author | Yoo, Sang-Yong | - |
dc.contributor.author | Lim, Do-Sun | - |
dc.contributor.author | Cho, Jang Hyun | - |
dc.contributor.author | Choi, Cheol Ung | - |
dc.contributor.author | Jeong, Myung Ho | - |
dc.contributor.author | Han, Kyoo-Rok | - |
dc.contributor.author | Cha, Kwang Soo | - |
dc.contributor.author | Lee, Sung Yun | - |
dc.contributor.author | Choi, Hyun-Hee | - |
dc.contributor.author | Choi, Jae Woong | - |
dc.contributor.author | Hyon, Min Su | - |
dc.contributor.author | Kim, Moo-Hyun | - |
dc.date.accessioned | 2021-08-31T08:46:12Z | - |
dc.date.available | 2021-08-31T08:46:12Z | - |
dc.date.created | 2021-06-19 | - |
dc.date.issued | 2020-03 | - |
dc.identifier.issn | 1941-7640 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/57462 | - |
dc.description.abstract | Background: There is limited data comparing the Xience everolimus-eluting stent (EES) and the Resolute zotarolimus-eluting stent (ZES) with the BioMatrix biolimus-eluting stent (BES). Methods: This open-label, randomized, noninferiority trial enrolled all-comer patients to be randomly treated with either BES, EES, or ZES in a 1:1:1 ratio in 15 centers across South Korea. The primary end point was a device-oriented composite outcome consisting of cardiac death, target-vessel myocardial infarction, and clinically indicated target lesion revascularization at 24 months. The BES was compared with the EES and the ZES by intention-to-treat analyses with a noninferiority margin of 3.8%, respectively. Results: Because of slow recruitment and low event rates, this trial was prematurely terminated after enrollment of 1935 (75%) of the intended 2580 patients. Of the 1911 patients randomized to either EES (n=638), BES (n=634), or ZES (n =639), the rate of device-oriented composite outcome was 3.6%, 2.2%, and 3.9%, respectively, at 24 months (BES versus EES: absolute risk difference -1.4% [upper limit of 1-sided 95% CI: -3.2%]; P (for noninferiority) P (for noninferiority) <0.001). Conclusions: The BES was noninferior to either the EES or the ZES in all-comer patients for device-oriented composite outcome at the 24-month follow-up. However, caution is advised regarding interpretation of these results due to the premature termination of this study. Registration: URL: ; Unique identifier: NCT01397175. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | - |
dc.subject | BIODEGRADABLE-POLYMER | - |
dc.subject | DURABLE-POLYMER | - |
dc.subject | CLINICAL-OUTCOMES | - |
dc.subject | ARTERY-DISEASE | - |
dc.subject | FOLLOW-UP | - |
dc.subject | INTERVENTION | - |
dc.subject | MULTICENTER | - |
dc.subject | ANGIOGRAPHY | - |
dc.subject | SORT | - |
dc.subject | VI | - |
dc.title | Randomized Comparison of Everolimus- and Zotarolimus-Eluting Coronary Stents With Biolimus-Eluting Stents in All-Comer Patients | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lim, Do-Sun | - |
dc.contributor.affiliatedAuthor | Choi, Cheol Ung | - |
dc.identifier.doi | 10.1161/CIRCINTERVENTIONS.119.008525 | - |
dc.identifier.scopusid | 2-s2.0-85081694196 | - |
dc.identifier.wosid | 000528853600006 | - |
dc.identifier.bibliographicCitation | CIRCULATION-CARDIOVASCULAR INTERVENTIONS, v.13, no.3 | - |
dc.relation.isPartOf | CIRCULATION-CARDIOVASCULAR INTERVENTIONS | - |
dc.citation.title | CIRCULATION-CARDIOVASCULAR INTERVENTIONS | - |
dc.citation.volume | 13 | - |
dc.citation.number | 3 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Cardiac & Cardiovascular Systems | - |
dc.subject.keywordPlus | BIODEGRADABLE-POLYMER | - |
dc.subject.keywordPlus | DURABLE-POLYMER | - |
dc.subject.keywordPlus | CLINICAL-OUTCOMES | - |
dc.subject.keywordPlus | ARTERY-DISEASE | - |
dc.subject.keywordPlus | FOLLOW-UP | - |
dc.subject.keywordPlus | INTERVENTION | - |
dc.subject.keywordPlus | MULTICENTER | - |
dc.subject.keywordPlus | ANGIOGRAPHY | - |
dc.subject.keywordPlus | SORT | - |
dc.subject.keywordPlus | VI | - |
dc.subject.keywordAuthor | coronary artery disease | - |
dc.subject.keywordAuthor | drug-eluting stent | - |
dc.subject.keywordAuthor | myocardial infarction | - |
dc.subject.keywordAuthor | percutaneous coronary intervention | - |
dc.subject.keywordAuthor | thrombosis | - |
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