Clinical Impact of Atypical Chest Pain and Diabetes Mellitus in Patients with Acute Myocardial Infarction from Prospective KAMIR-NIH Registry
DC Field | Value | Language |
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dc.contributor.author | Lee, Jun-Won | - |
dc.contributor.author | Moon, Jin Sil | - |
dc.contributor.author | Kang, Dae Ryong | - |
dc.contributor.author | Lee, Sang Jun | - |
dc.contributor.author | Son, Jung-Woo | - |
dc.contributor.author | Youn, Young Jin | - |
dc.contributor.author | Ahn, Sung Gyun | - |
dc.contributor.author | Ahn, Min-Soo | - |
dc.contributor.author | Kim, Jang-Young | - |
dc.contributor.author | Yoo, Byung-Su | - |
dc.contributor.author | Lee, Seung-Hwan | - |
dc.contributor.author | Kim, Ju Han | - |
dc.contributor.author | Jeong, Myung Ho | - |
dc.contributor.author | Park, Jong-Seon | - |
dc.contributor.author | Chae, Shung Chull | - |
dc.contributor.author | Hur, Seung Ho | - |
dc.contributor.author | Cho, Myeng-Chan | - |
dc.contributor.author | Rha, Seung Woon | - |
dc.contributor.author | Cha, Kwang Soo | - |
dc.contributor.author | Chae, Jei Keon | - |
dc.contributor.author | Choi, Dong-Ju | - |
dc.contributor.author | Seong, In Whan | - |
dc.contributor.author | Oh, Seok Kyu | - |
dc.contributor.author | Hwang, Jin Yong | - |
dc.contributor.author | Yoon, Junghan | - |
dc.date.accessioned | 2021-08-31T11:25:39Z | - |
dc.date.available | 2021-08-31T11:25:39Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2020-02 | - |
dc.identifier.issn | 2077-0383 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/57806 | - |
dc.description.abstract | Atypical chest pain and diabetic autonomic neuropathy attract less clinical attention, leading to underdiagnosis and delayed treatment. To evaluate the long-term clinical impact of atypical chest pain and diabetes mellitus (DM), we categorized 11,159 patients with acute myocardial infarction (AMI) from the Korea AMI-National Institutes of Health between November 2011 and December 2015 into four groups (atypical DM, atypical non-DM, typical DM, and typical non-DM). The primary endpoint was defined as patient-oriented composite endpoint (POCE) at 2 years including all-cause death, any myocardial infarction (MI), and any revascularization. Patients with atypical chest pain showed higher 2-year mortality than those with typical chest pain in both DM (29.5% vs. 11.4%, p < 0.0001) and non-DM (20.4% vs. 6.3%, p < 0.0001) groups. The atypical DM group had the highest risks of POCE (hazard ratio (HR) 1.76, 95% confidence interval (CI) 1.48-2.10), all-cause death (HR 2.23, 95% CI 1.80-2.76) and any MI (HR 2.34, 95% CI 1.51-3.64) in the adjusted model. In conclusion, atypical chest pain was significantly associated with mortality in patients with AMI. Among four groups, the atypical DM group showed the worst clinical outcomes at 2 years. Application of rapid rule in/out AMI protocols would be beneficial to improve clinical outcomes. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | MDPI | - |
dc.subject | AUTONOMIC DYSFUNCTION | - |
dc.subject | MORTALITY | - |
dc.subject | RISK | - |
dc.subject | DIAGNOSIS | - |
dc.subject | SYMPTOMS | - |
dc.subject | CARE | - |
dc.title | Clinical Impact of Atypical Chest Pain and Diabetes Mellitus in Patients with Acute Myocardial Infarction from Prospective KAMIR-NIH Registry | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Rha, Seung Woon | - |
dc.identifier.doi | 10.3390/jcm9020505 | - |
dc.identifier.wosid | 000518823000217 | - |
dc.identifier.bibliographicCitation | JOURNAL OF CLINICAL MEDICINE, v.9, no.2 | - |
dc.relation.isPartOf | JOURNAL OF CLINICAL MEDICINE | - |
dc.citation.title | JOURNAL OF CLINICAL MEDICINE | - |
dc.citation.volume | 9 | - |
dc.citation.number | 2 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.subject.keywordPlus | AUTONOMIC DYSFUNCTION | - |
dc.subject.keywordPlus | MORTALITY | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordPlus | DIAGNOSIS | - |
dc.subject.keywordPlus | SYMPTOMS | - |
dc.subject.keywordPlus | CARE | - |
dc.subject.keywordAuthor | chest pain | - |
dc.subject.keywordAuthor | diabetes | - |
dc.subject.keywordAuthor | myocardial infarction | - |
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