Current Anticoagulant Usage Patterns and Determinants in Korean Patients with Nonvalvular Atrial Fibrillation
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ha, Hyun Su | - |
dc.contributor.author | Kim, Joongmin | - |
dc.contributor.author | Lee, Young Soo | - |
dc.contributor.author | Kim, Tae-Hoon | - |
dc.contributor.author | Lee, Jung Myung | - |
dc.contributor.author | Park, Junbeom | - |
dc.contributor.author | Park, Jin-Kyu | - |
dc.contributor.author | Kang, Ki-Woon | - |
dc.contributor.author | Shim, Jaemin | - |
dc.contributor.author | Uhm, Jae-Sun | - |
dc.contributor.author | Park, Hyung Wook | - |
dc.contributor.author | Cha, Myung-Jin | - |
dc.contributor.author | Choi, Eue-Keun | - |
dc.contributor.author | Kim, Jun | - |
dc.contributor.author | Kim, Jin-Bae | - |
dc.contributor.author | Kim, Changsoo | - |
dc.contributor.author | Joung, Boyoung | - |
dc.date.accessioned | 2021-08-31T11:36:09Z | - |
dc.date.available | 2021-08-31T11:36:09Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2020-02 | - |
dc.identifier.issn | 0513-5796 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/57875 | - |
dc.description.abstract | Purpose: Stroke prevention in patients with atrial fibrillation (AF) is influenced by many factors. Using a contemporary registry, we evaluated variables associated with the use of warfarin or direct oral anticoagulants (OACs). Materials and Methods: In the prospective multicenter CODE-AF registry, 10529 patients with AF were evaluated. Multivariate analyses were performed to identify variables associated with the use of anticoagulants. Results: The mean age of the patients was 66.9 +/- 14.4 years, and 64.9% were men. The mean CHA(2)DS(2)-VASc and HAS-BLED scores were 2.6 +/- 1.7 and 1.8 +/- 1.1, respectively. In patients with high stroke risk (CHA(2) DS2-VASc >= 2) OACs were used in 83.2%, including direct OAC in 68.8%. The most important factors for non-OAC treatment were end-stage renal disease [odds ratio (OR) 0.27; 95% confidence interval (CO: 0.19-0.40], myocardial infarct (OR 0.53; 95% CI: 0.40-0.72), and major bleeding (OR 0.57; 95% CI: 0.390.84). Female sex (OR 1.40; 95% CI: 1.21-1.61), cancer (OR 1.78; 95% CI: 1.38-2.29), and smoking (OR 1.60; 95% CI: 1.15-2.24) were factors favoring direct OAC use over warfarin. Among patients receiving OACs, the rate of combined antiplatelet agents was 7.8%. However, 73.6% of patients did not have any indication for a combination of antiplatelet agents. Conclusion: Renal disease and history of valvular heart disease were associated with warfarin use, while cancer and smoking status were associated with direct OAC use in high stroke risk patients. The combination of antiplatelet agents with OAC was prescribed in 73.6% of patients without definite indications recommended by guidelines. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | YONSEI UNIV COLL MEDICINE | - |
dc.subject | ANTAGONIST ORAL ANTICOAGULANTS | - |
dc.subject | ANTITHROMBOTIC THERAPY | - |
dc.subject | STROKE PREVENTION | - |
dc.subject | ASIAN PATIENTS | - |
dc.subject | MANAGEMENT | - |
dc.subject | RISK | - |
dc.subject | MEDICATION | - |
dc.subject | DABIGATRAN | - |
dc.subject | GUIDELINE | - |
dc.subject | ADHERENCE | - |
dc.title | Current Anticoagulant Usage Patterns and Determinants in Korean Patients with Nonvalvular Atrial Fibrillation | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Shim, Jaemin | - |
dc.identifier.doi | 10.3349/ymj.2020.61.2.120 | - |
dc.identifier.scopusid | 2-s2.0-85078690207 | - |
dc.identifier.wosid | 000510614300002 | - |
dc.identifier.bibliographicCitation | YONSEI MEDICAL JOURNAL, v.61, no.2, pp.120 - 128 | - |
dc.relation.isPartOf | YONSEI MEDICAL JOURNAL | - |
dc.citation.title | YONSEI MEDICAL JOURNAL | - |
dc.citation.volume | 61 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 120 | - |
dc.citation.endPage | 128 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002552955 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.subject.keywordPlus | ANTAGONIST ORAL ANTICOAGULANTS | - |
dc.subject.keywordPlus | ANTITHROMBOTIC THERAPY | - |
dc.subject.keywordPlus | STROKE PREVENTION | - |
dc.subject.keywordPlus | ASIAN PATIENTS | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordPlus | MEDICATION | - |
dc.subject.keywordPlus | DABIGATRAN | - |
dc.subject.keywordPlus | GUIDELINE | - |
dc.subject.keywordPlus | ADHERENCE | - |
dc.subject.keywordAuthor | Atrial fibrillation | - |
dc.subject.keywordAuthor | anticoagulation | - |
dc.subject.keywordAuthor | pattern | - |
dc.subject.keywordAuthor | determinant | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.