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Intraoperative imaging based on common-path time-domain reflectometry for brain tumor surgery

Authors
Han, Jae-HoCha, Jaepyeong
Issue Date
2020
Publisher
WROCLAW UNIV SCIENCE TECHNOLOGY
Keywords
optical coherence tomography; intraoperative imaging; reflectometry; endoscopy
Citation
OPTICA APPLICATA, v.50, no.2, pp.223 - 227
Indexed
SCIE
SCOPUS
Journal Title
OPTICA APPLICATA
Volume
50
Number
2
Start Page
223
End Page
227
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/59009
DOI
10.37190/oa200205
ISSN
0078-5466
Abstract
Minimally invasive intraoperative imaging plays a crucial role in delicate microsurgeries for precise operation monitoring in which fiber optic imaging can be considered as an endoscopy and surgical proximity guidance tool due to its compactness. This paper presents a near-infrared time -domain reflectometric common-path optical coherence tomography imaging technique using a bare-fiber probe mounted directly on a scanning galvanometer. The common-path setup allows the use of a freely adjustable optical path length and a disposable fiber probe, as well as eliminating the need for an additional dedicated reference optical path. Experimental results demonstrate clear discrimination between the brain tumor tissue and the normal tissue for mouse brains with the images acquired in real-time over a wide area. The proposed method enables real-time and in situ visualization of tumor resection for intraoperative imaging, and this study demonstrates the feasibility of its application to micro surgical interventions.
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