Animal models for the risk assessment of viral pandemic potentialAnimal models for the risk assessment of viral pandemic potential
- Other Titles
- Animal models for the risk assessment of viral pandemic potential
- Authors
- 박미숙; 김진일; 배준용; 박만성
- Issue Date
- 2020
- Publisher
- 한국실험동물학회
- Keywords
- Animal model; Pandemic; Pathogenicity; Transmission; Virus; Zoonosis
- Citation
- Laboratory Animal Research, v.36, no.2, pp.73 - 87
- Indexed
- KCI
- Journal Title
- Laboratory Animal Research
- Volume
- 36
- Number
- 2
- Start Page
- 73
- End Page
- 87
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/59163
- DOI
- 10.1186/s42826-020-00040-6
- ISSN
- 1738-6055
- Abstract
- Pandemics affect human lives severely and globally. Experience predicts that there will be a pandemic for sure although the time is unknown. When a viral epidemic breaks out, assessing its pandemic risk is an important part of the process that characterizes genomic property, viral pathogenicity, transmission in animal model, and so forth. In this review, we intend to figure out how a pandemic may occur by looking into the past influenza pandemic events. We discuss interpretations of the experimental evidences resulted from animal model studies and extend implications of viral pandemic potentials and ingredients to emerging viral epidemics. Focusing on the pandemic potential of viral infectious diseases, we suggest what should be assessed to prevent global catastrophes from influenza virus, Middle East respiratory syndrome coronavirus, dengue and Zika viruses.
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- Appears in
Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
- Graduate School > Department of Biomedical Sciences > 1. Journal Articles
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