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Origami-paper-based device for microvesicle/exosome preconcentration and isolation

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dc.contributor.authorKim, Hyerin-
dc.contributor.authorLee, Kyu Hyoung-
dc.contributor.authorHan, Sung Il-
dc.contributor.authorLee, Dongho-
dc.contributor.authorChung, Seok-
dc.contributor.authorLee, Dohwan-
dc.contributor.authorLee, Jeong Hoon-
dc.date.accessioned2021-08-31T21:23:58Z-
dc.date.available2021-08-31T21:23:58Z-
dc.date.created2021-06-18-
dc.date.issued2019-12-07-
dc.identifier.issn1473-0197-
dc.identifier.urihttps://scholar.korea.ac.kr/handle/2021.sw.korea/60943-
dc.description.abstractMicrovesicles and exosomes are promising liquid biopsy biomarkers. However, conventional isolation techniques damage and contaminate the biomarkers. We developed an origami-paper-based device for effective isolation of biomarkers with less damage and in fewer steps. The multi-folded device enables the preconcentration of the microvesicles/exosomes on specific layers (similar to 5-fold) by the ion concentration polarization technique and they were simply isolated from the rest of the sample by unfolding the device.-
dc.languageEnglish-
dc.language.isoen-
dc.publisherROYAL SOC CHEMISTRY-
dc.subjectLIQUID BIOPSY-
dc.subjectEXTRACELLULAR VESICLES-
dc.subjectEXOSOME ISOLATION-
dc.titleOrigami-paper-based device for microvesicle/exosome preconcentration and isolation-
dc.typeArticle-
dc.contributor.affiliatedAuthorChung, Seok-
dc.identifier.doi10.1039/c9lc00796b-
dc.identifier.scopusid2-s2.0-85075228091-
dc.identifier.wosid000498230700001-
dc.identifier.bibliographicCitationLAB ON A CHIP, v.19, no.23, pp.3917 - 3921-
dc.relation.isPartOfLAB ON A CHIP-
dc.citation.titleLAB ON A CHIP-
dc.citation.volume19-
dc.citation.number23-
dc.citation.startPage3917-
dc.citation.endPage3921-
dc.type.rimsART-
dc.type.docTypeArticle-
dc.description.journalClass1-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaBiochemistry & Molecular Biology-
dc.relation.journalResearchAreaChemistry-
dc.relation.journalResearchAreaScience & Technology - Other Topics-
dc.relation.journalResearchAreaInstruments & Instrumentation-
dc.relation.journalWebOfScienceCategoryBiochemical Research Methods-
dc.relation.journalWebOfScienceCategoryChemistry, Multidisciplinary-
dc.relation.journalWebOfScienceCategoryChemistry, Analytical-
dc.relation.journalWebOfScienceCategoryNanoscience & Nanotechnology-
dc.relation.journalWebOfScienceCategoryInstruments & Instrumentation-
dc.subject.keywordPlusLIQUID BIOPSY-
dc.subject.keywordPlusEXTRACELLULAR VESICLES-
dc.subject.keywordPlusEXOSOME ISOLATION-
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공과대학 (기계공학부)
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