Long-term outcomes of immediate autologous breast reconstruction after definite adjuvant therapy in intermediate and locally advanced breast cancer
DC Field | Value | Language |
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dc.contributor.author | Yoon, Won Sup | - |
dc.contributor.author | Rim, Chai Hong | - |
dc.contributor.author | Yang, Dae Sik | - |
dc.contributor.author | Lee, Jung Ae | - |
dc.contributor.author | Son, Gil Soo | - |
dc.contributor.author | Chang, Young Woo | - |
dc.contributor.author | Woo, Sang Uk | - |
dc.contributor.author | Kim, Deok-Woo | - |
dc.contributor.author | Dhong, Eun-Sang | - |
dc.date.accessioned | 2021-08-31T22:41:06Z | - |
dc.date.available | 2021-08-31T22:41:06Z | - |
dc.date.created | 2021-06-19 | - |
dc.date.issued | 2019-12 | - |
dc.identifier.issn | 2305-5839 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/61363 | - |
dc.description.abstract | Background: To analyze oncologic outcomes and reconstruction quality in locally advanced stage breast cancer after performing immediate autologous breast reconstruction (IABR). Methods: From 2007 to 2014, data of patients aged <= 70 years old with stage II-III breast cancer who received total mastectomy (TM) were extracted from medical records. Exclusion criteria were: previous contralateral breast cancer, follow-up loss before adjuvant therapy completion, and artificial reconstruction. Patients were divided into two groups: (I) TM alone, and (II) TM + IABR. Overall survival (OS) and locoregional recurrence free survival (LRRFS) were calculated. Times of minor revision, abnormal image findings in breast, and change of breast height were observed. Results: Sixty-one of 188 patients received IABR after TM. Stage IIIB-C was the most important prognostic factor for OS (P<0.001) and LRRFS (P<0.001). For stage II, five-year TM and TM + IABR OS rates were 96.8% and 100% (P=0.324), respectively. For stage IIIB-C, five-year TM and TM + IABR OS rates were 57.6% and 62.5% (P=0.544), respectively. For stage II, five-year TM and TM + IABR LRRFS were 98.1% and 95.7% (P=0.998), respectively. For stage IIIB-C, five-year TM and TM + IABR LRRFS were 70.8% and 62.5% (P=0.378), respectively. Two major complications were observed after IABR. Minor revisions, abnormal image findings, and change of breast height were common without showing significant relation with adjuvant radiotherapy or tumor stage. Conclusions: IABR showed feasible oncologic outcomes in 5-year follow-up. Adjuvant radiotherapy had little effect on quality of reconstruction. However, IABR in advanced stage should be cautiously applied considering expected survival and minor problems after IABR. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | AME PUBL CO | - |
dc.subject | POSTMASTECTOMY RADIATION-THERAPY | - |
dc.subject | NEOADJUVANT CHEMOTHERAPY | - |
dc.subject | LATISSIMUS-DORSI | - |
dc.subject | MASTECTOMY | - |
dc.subject | RADIOTHERAPY | - |
dc.subject | FLAP | - |
dc.subject | COMPLICATIONS | - |
dc.subject | VOLUME | - |
dc.subject | IMPACT | - |
dc.title | Long-term outcomes of immediate autologous breast reconstruction after definite adjuvant therapy in intermediate and locally advanced breast cancer | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Yoon, Won Sup | - |
dc.contributor.affiliatedAuthor | Rim, Chai Hong | - |
dc.contributor.affiliatedAuthor | Yang, Dae Sik | - |
dc.contributor.affiliatedAuthor | Son, Gil Soo | - |
dc.contributor.affiliatedAuthor | Chang, Young Woo | - |
dc.contributor.affiliatedAuthor | Woo, Sang Uk | - |
dc.contributor.affiliatedAuthor | Kim, Deok-Woo | - |
dc.contributor.affiliatedAuthor | Dhong, Eun-Sang | - |
dc.identifier.doi | 10.21037/atm.2019.11.129 | - |
dc.identifier.wosid | 000503257700032 | - |
dc.identifier.bibliographicCitation | ANNALS OF TRANSLATIONAL MEDICINE, v.7, no.23 | - |
dc.relation.isPartOf | ANNALS OF TRANSLATIONAL MEDICINE | - |
dc.citation.title | ANNALS OF TRANSLATIONAL MEDICINE | - |
dc.citation.volume | 7 | - |
dc.citation.number | 23 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.relation.journalResearchArea | Oncology | - |
dc.relation.journalResearchArea | Research & Experimental Medicine | - |
dc.relation.journalWebOfScienceCategory | Oncology | - |
dc.relation.journalWebOfScienceCategory | Medicine, Research & Experimental | - |
dc.subject.keywordPlus | POSTMASTECTOMY RADIATION-THERAPY | - |
dc.subject.keywordPlus | NEOADJUVANT CHEMOTHERAPY | - |
dc.subject.keywordPlus | LATISSIMUS-DORSI | - |
dc.subject.keywordPlus | MASTECTOMY | - |
dc.subject.keywordPlus | RADIOTHERAPY | - |
dc.subject.keywordPlus | FLAP | - |
dc.subject.keywordPlus | COMPLICATIONS | - |
dc.subject.keywordPlus | VOLUME | - |
dc.subject.keywordPlus | IMPACT | - |
dc.subject.keywordAuthor | Breast cancer | - |
dc.subject.keywordAuthor | mastectomy | - |
dc.subject.keywordAuthor | radiotherapy | - |
dc.subject.keywordAuthor | reconstruction | - |
dc.subject.keywordAuthor | survival | - |
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