Nafion-stabilized two-dimensional transition metal carbide (Ti3C2TX MXene) as a high-performance electrochemical sensor for neurotransmitter

Abstract

Herein, we demonstrate the selective sensing of Dopamine (DA), an important neurotransmitter, by using Nafion-stabilized two-dimensional transition metal carbides (Ti3C2Tx MXenes). Ti3C2Tx was deposited on a glassy carbon electrode followed by Nafion coating to achieve a robust sensitivity (similar to 3 nM), good selectivity, wide detection window (0.015-10 mu M), high stability, reproducibility, and outstanding recoveries for DA detection in real samples. MXene-based biosensor exhibited much better electrochemical performance when compared with reduced graphene oxide-based biosensor under similar experimental conditions due to the MXenes good electrical conductivity and negatively charged surface which assisted in the selective and sensitive detection of DA. (C) 2019 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.